BACKGROUND The assessment and classification of trochlear dysplasia in pediatric patients has yet to be well documented or validated. PURPOSE To examine several different measurements/classifications of trochlear dysplasia in skeletally immature patients to assess inter- and intraobserver reliability and to determine which best correlates with patellar instability. STUDY DESIGN Cohort study...

The alpha(4) integrins alpha(4)beta(7) and alpha(4)beta(1), and their ligands mucosal vascular addressin cell adhesion molecule 1 (MAdCAM-1) and VCAM-1, have diverse functions, including roles in the formation of secondary lymphoid tissues at early time points during the colonization and clustering of the fetal lymphoid tissue inducer (LTi) cells and at later time points during the recruitment ...

PURPOSE Optical and neural sources of short wavelength sensitivity should be separated in the assessment of the results of blue-on-yellow (B/Y) perimetry. It has been shown previously that lens autofluorescence is related directly to lens yellowing and age. The aim of this study was to find out if B/Y perimetry results can be better corrected by using lens fluorometry than by age. METHODS The...

OBJECTIVE The outcomes of open surgical or endovascular intervention for limb-threatening ischemia (LTI) involving the infrapopliteal vessels are dependent on complex anatomic, demographic, and disease factors. To assist in decision-making, we used the Vascular Quality Initiative (VQI) to derive a model using only preoperatively available factors to predict important outcomes for open or endova...

Model order reduction (MOR) is here understood as a computational technique to reduce the order of a dynamical system described by a set of ordinary or differential-algebraic equations (ODEs or DAEs) to facilitate or enable its simulation, the design of a controller, or optimization and design of the physical system modeled. It focuses on representing the map from inputs into the system to its ...

Every day, thousands of patients who present to emergency departments (EDs) require tracheal intubation for optimal care. Most acute intubations are performed using rapid sequence intubation (RSI), with the administration of an intravenous sedative followed by a paralytic agent, to obtain the best chance for successful intubation. Premedication with various agents prior to RSI when certain cond...

The influence of lower limb venous compliance on orthostatic vasovagal syncope (VVS) is uncertain. The most widespread technique to calculate venous compliance uses a nonphysiological quadratic regression equation. Our aim was therefore to construct a physiologically derived venous wall model (VWM) for calculation of calf venous compliance and to determine the effect of venous compliance on tol...