نتایج جستجو برای: ltb
تعداد نتایج: 643 فیلتر نتایج به سال:
BACKGROUND & AIM Screening for latent tuberculosis (LTB) is recommended before starting anti-TNF-alpha therapy. We compared the performance of Quantiferon-TB Gold (QFT-G) with the tuberculin skin test (TST) for the screening of LTB in a population of inflammatory bowel disease (IBD) patients who were candidates for anti-TNF-α therapy. METHODS Ninety-two IBD patients who were candidates for an...
background: prompt diagnosis and treatment of latent tuberculosis (tb) infection (ltbi) are needed to control tb. the aim of the study was to compare the performance of quanti feron-tb test (qft) with conventional tst for the diagnosis of ltbi. methods: in this analytical - comparison study, we enrolled 87 nurses working in teaching hospitals in ahvaz. all study subjects were tested by tst. ts...
The glomeruli are very sensitive to inflammatory injury. Many studies are currently being done on cytokines and inflammatory mediators in various types of renal diseases. The spectrum of known proinflammatory compounds originating from glomeruli has expanded recently to include arachidonic acid-derived lipoxygenase metabolites and platelet activating factor (PAF) (1, 2). In recent experimental ...
Cyclooxygenases (COXs) are the key enzymes in the biosynthesis of prostanoids. COX-1 is a constitutive enzyme while the expression of COX-2 is highly stimulated in the event of inflammatory processes, leading to the production of large amounts of prostaglandins (PGs), in particular PGE(2) and PGI(2), which are pro-inflammatory mediators. Lipoxygenases (LOXs) are enzymes that produce hydroxy aci...
Dendritic cells (DC) are important APCs that control allergen-induced airway responses by interacting directly with T cells. Leukotriene B(4) (LTB(4)), interacting with its high-affinity receptor, LTB(4) receptor 1 (BLT1), is known to attract and activate leukocytes during inflammation. We have previously shown that BLT1 expression on Ag-primed T cells is required for the development of airway ...
The heat-labile toxins (LT) produced by enterotoxigenic Escherichia coli display adjuvant effects to coadministered antigens, leading to enhanced production of serum antibodies. Despite extensive knowledge of the adjuvant properties of LT derivatives, including in vitro-generated non-toxic mutant forms, little is known about the capacity of these adjuvants to modulate the epitope specificity of...
AIMS To assess whether a strategy of invasive management without stents in selected acute coronary syndrome (ACS) patients with a large thrombus burden (LTB) might be feasible and safe. METHODS AND RESULTS We performed a prospective non-randomised observational cohort study of invasive treatment decisions guided by optical coherence tomography (OCT) in selected ACS patients with LTB. Among 85...
All three cytochrome P450 1 (CYP1) monooxygenases are believed to participate in lipid mediator biosynthesis and/or their local inactivation; however, distinct metabolic steps are unknown. We used multiple-reaction monitoring and liquid chromatography-UV coupled with tandem mass spectrometry-based lipid-mediator metabololipidomics to identify and quantify three lipid-mediator metabolomes in bas...
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