Istihalah and istihlak are not an extraterrestrial subject have been debated over centuries among shariah scholars. Halal Pharmaceutical had clearly explained that must comply with prerequisite to be endorsed as halal compliance medicine. However, this industry often faces unmatched medicine which able heal deteriorated diseases such thrombosis or embolism require second opinion by Shariah The ...

BACKGROUND Patients with acute ischemic stroke and large artery occlusive disease (LAOD) have an increased risk for early neurologic deterioration (END) due to progressive stroke, early recurrent ischemic stroke(ERIS), or symptomatic intracranial cerebral hemorrhage(SICH). Low-molecular-weight heparin (LMWH)has been widely advocated to prevent venous thromboembolism,but its risks and benefits i...

Hemodynamic and hematologic effects of protamine reversal of low molecular weight heparin (LMWH) anticoagulation with and without protamine pretreatment, as well as reversal of anticoagulation with unfractionated standard heparin (SH), were studied in canine subjects. Protamine reversal caused less severe thrombocytopenia in the two LMWH groups compared to SH animals, while neutropenia occurred...

BACKGROUND As acute lung injury (ALI) caused high mortality rate, it is important to explore the protection and treatment of ALI. The aim of the current study is to evaluate the effect of low molecular weight heparin (LMWH) nebulization on attenuating acute lung injury and the associated mechanism. METHODS The arterial blood gas, total protein content in bronchoalveolar lavage fluid, lung wet...

EPIDURAL catheters are commonly used in today’s anesthetic practice, and complications are rare. However, hematomas within the spinal canal leading to compression of the spinal cord remain a major concern. In particular, anticoagulation and bleeding disorders are considered to be risk factors for hematoma formation after neuroaxial blockade. We report a case of paraplegia that developed after r...

Anticoagulation drugs are frequently used to prevent deep vein thrombosis in high-risk patients. Subcutaneous low molecular weight heparin (LMWH) is increasingly used in both hospitalized patients and outpatient settings. This necessitates familiarity of both health care providers and patients with such treatment and vigilance on possible complications. Here we present a case of hematoma of rec...

2.1. In patients with acute DVT of the leg treated with vitamin K antagonist (VKA) therapy, we Background: This article addresses the treatment of VTE disease. Methods: We generated strong (Grade 1) and weak (Grade 2) recommendations based on highquality (Grade A), moderate-quality (Grade B), and low-quality (Grade C) evidence. Results: For acute DVT or pulmonary embolism (PE), we recommend ini...

To the Editor: A study in Canada and New Zealand (Kearon et al.) suggested that fixed-dose unmonitored subcutaneous (SC) unfractionated heparin (UFH) is as effective and safe as low-molecular-weight heparin (LMWH) for the acute treatment of venous thrombo-embolism (VTE). While this trial has limitations, it provides evidence to support the use of SC UFH in a resource-constrained environment. Ho...

Low-molecular-weight heparins (LMWH) appear to prolong survival of patients with cancer. Such a beneficial effect is thought to be associated with interruption of molecular mechanisms involving the heparan sulfate (HS) chains of cell surface and extracellular matrix proteoglycans (HSPGs), growth factors and their receptors, heparanase, and selectins. The beneficial effects of heparin species co...