This data article shows how the recombinant Chinese Hamster Ovary (CHO) cells are located in the interstices of the matrix fibers of a CellTank bioreactor after completion of a perfusion culture, supporting the article entitled "Very high cell density perfusion of CHO cells anchored in a non-woven matrix-based bioreactor" by Zhang et al. [1]. It provides a visualization of the cell distribution...

Citation: Jakobs G, Labrenz M, Rehder G, Hietanen S, Kießlich K, Vogts A, Blumenberg M and Schmale O (2016) A Bioreactor Approach to Investigate the Linkage between Methane Oxidation and Nitrate/Nitrite Reduction in the Pelagic Oxic-Anoxic Transition Zone of the Central Baltic Sea. Front. Mar. Sci. 3:145. doi: 10.3389/fmars.2016.00145 A Bioreactor Approach to Investigate the Linkage between Met...

We study the stochastic model for bioremediation in a bioreactor with ideal mixing. The dynamics of the examined system is described by stochastic differential equations. We consider an optimal control problem with quadratic costs functional for the linearized model of a well-stirred bioreactor. The optimal control is based on the optimal robust state estimates. The approximate optimal solution...

Enzyme surface concentration and permeate stream obtained in the membrane module with a dynamically formed biocatalyst layer were determined experimentally using two different, polymeric membranes. Correlations were formulated to calculate these values. It was found that their variability range was so big that when controlling the transmembrane pressure and turbulence of a retentate stream, the...

Abstract Control strategy development for fed-batch bioreactor (FBBR) plays an important role in the improvement of polyhydroxyalkanoate (PHA) production. To develop a feeding PHA production large-scale FBBR, optimization-based control scheme that considers nutrient dispersion is proposed this work. A coupled partial differential equations and ordinary equation model to describe axial-dispersed...

In recent years, there has been a growing interest in bioreactors, which utilise immobilised enzymes and cells in order to improve the bioprocess productivity. In fact, there are many specific advantages of the immobilised systems in comparison with the more conventional systems, in which the bio-agents are suspended freely (cells) or dissolved in a bulk aqueous medium (enzymes): • high cell de...

The present work deals with the kinetics of rifamycins production and degradation by Amycolatopsis mediterranei in submerged culture using industrial medium. Cultivations were conducted in shake flasks and stirred tank bioreactor to evaluate the influence of transfer of process to higher scale on overall process kinetics and to obtain better understanding for the kinetics of rifamycins producti...

An economical bioreactor designed for evaluating the biogas potential of particulate biomass is described. The bioreactor uses a simple stirring apparatus, called the Bordeaux stirrer, to enable gas-tight mixing of fermentation cultures. The apparatus consists of a low-rpm motor connected to a bent steel stir rod, which is placed in a length of flexible plastic tubing inserted through a rubber ...

Biofiltration for volatile organic compound control in waste gas streams is best operated at steady contaminant loadings. To provide long-term stable operation of a biofilter under adverse contaminant feeding conditions, an integrated bioreactor system with a gas separation membrane module installed after a biofilter was proposed for styrene treatment. Styrene was treated effectively, with aver...