نتایج جستجو برای: localized pemphigus foliaceus

تعداد نتایج: 106641  

Journal: :Canadian journal of health technologies 2023


 We did not find any evidence regarding the clinical effectiveness and safety of alternative treatments to IV immunoglobulin (IVIg) compared IVIg or placebo for bullous pemphigoid (BP) pemphigus vulgaris (PV) foliaceus (PF) that met our inclusion criteria this review.
 identified 6 consensus guidelines presenting treatment algorithms BP (3 guidelines) PV PF guidelines). All recommend...

2013
Athanasios Mavropoulos Timoklia Orfanidou Christos Liaskos Daniel S. Smyk Vassiliki Spyrou Lazaros I. Sakkas Eirini I. Rigopoulou Dimitrios P. Bogdanos

p38 mitogen activated protein kinase (p38 MAPK) signaling plays a major role in the modulation of immune-mediated inflammatory responses and therefore has been linked with several autoimmune diseases. The extent of the involvement of p38 MAPK in the pathogenesis of autoimmune blistering diseases has started to emerge, but whether it pays a critical role is a matter of debate. The activity of p3...

Journal: :British Journal of Dermatology 2021

Background Pemphigus is a severe bullous autoimmune skin disease. foliaceus (PF) characterized by antidesmoglein (Dsg) 1 IgG causing epidermal blistering; mucosal pemphigus vulgaris (mPV) anti-Dsg3 inducing erosions in the mucosa; and mucocutaneous (PV) affecting both, with autoantibodies targeting Dsg1 Dsg3. Objectives To characterize Ca2+ flux pathway delineate its importance pathogenesis cli...

Journal: :Journal of the Chinese Medical Association : JCMA 2007
Cheng-Hung Huang Chih-Chiang Chen Chi-Jui Wang Yun-Ting Chang Han-Nan Liu

BACKGROUND Pemphigus is an acquired autoimmune intraepidermal blistering disease that is divided into 2 major subtypes: pemphigus vulgaris (PV) and pemphigus foliaceus (PF). Patients with pemphigus have circulating anti-desmoglein (Dsg)1 and/or anti-Dsg3 IgG autoantibodies. Recently, a novel commercial enzyme-linked immunosorbent assay (ELISA) against Dsg1 and Dsg3 has been established and foun...

2015
Patrick M. Brunner Doris WEISS Robin RISTL Johannes GRISS Christine BANGERT Dagmar FOEDINGER Georg STINGL Patrick M. BRUNNER

© 2015 The Authors. doi: 10.2340/00015555-2023 Journal Compilation © 2015 Acta Dermato-Venereologica. ISSN 0001-5555 Detecting serum-autoantibodies by anti-Desmoglein-1 (anti-Dsg1) and anti-Dsg3 ELISAs as well as indirect immunofluorescence (IIF) are established complementary methods to diagnose pemphigus. Whether autoantibody levels also reflect clinical disease activity is still a matter of d...

Journal: :Journal of immunology 2012
Ye Qian Joseph S Jeong Mike Maldonado Jesus G Valenzuela Regis Gomes Clarissa Teixeira Flor Evangelista Bahjat Qaqish Valeria Aoki Gunter Hans Evandro A Rivitti Donald Eaton Luis A Diaz

The environmental factors that contribute to the development of autoimmune diseases are largely unknown. Endemic pemphigus foliaceus in humans, known as Fogo Selvagem (FS) in Brazil, is mediated by pathogenic IgG4 autoantibodies against desmoglein 1 (Dsg1). Clusters of FS overlap with those of leishmaniasis, a disease transmitted by sand fly (Lutzomyia longipalpis) bites. In this study, we show...

Journal: :Journal of Investigative Dermatology Symposium Proceedings 2004

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