Tumoral calcinosis is a rare condition characterized by deposits of calcium hydroxyapatite crystals in periarticular soft tissues. Three clinical settings are possible: complication of renal dialysis, hereditary and sporadic. The condition more commonly affects adults, is rare in children and extremely uncommon in infants. A case of sporadic tumoral calcinosis of the hip is reported in a six-ye...

Histology is the diagnosis gold standard. Conventional biopsy presents artifacts, delays, or human bias. Digital histology includes automation and improved diagnosis. It digitalizes microscopic images of histological samples analyzes similar parameters. The present approach proposes novel use phase contrast in clinical digital to improve label-free fresh tissue slices prevents processing artifa...

primary non-hodgkin lymphoma of liver is a very rare malignancy. here we report a case of primary hepatic burkitt’s lymphoma in a 34-year old man who was known case of acquired immunodeficiency syndrome (aids) and presented with weight loss, abdominal pain, and fever. positive laboratory findings were mild anemia and elevated levels of lactate dehydrogenase (ldh) and alkaline phosphatase (alp)....

Background: Transarterial radioembolization (TARE) relies on directly injected 90Y- or 166Ho-loaded microspheres in the hepatic arteries. The activity to be is generally based pre-TARE 99mTc-macro-aggregated-albumin (MAA) imaging, while actual dose distribution post-treatment images. volume of interest (VOIs) propagation methods (i.e., rigid and deformable) from pre- post-TARE imaging might aff...

DOI: 10.7247/jiumf.2012.19.1.40_45 Background: Chronic Myelogenous Leukemia (CML) is a myeloproliferative disorder characterized by, overproduction of myeloid cells. Hydroxyurea is an antimetabolite which is commonly used in myeloproliferative syndromes. Reported skin changes related to hydroxyurea therapy may range form xerosis to mucocutaneous cancers. Aim: In this study, our aim was to under...

BACKGROUND Calcinosis cutis is the cutaneous deposition of calcium salts. Tumoral Calcinosis is a condition consisting of massive subcutaneous deposits of calcium salts often overlying large joints in otherwise healthy patients. OBJECTIVE To describe the characteristics of a series of patients with Tumoral Calcinosis in the Gurage Zone of Central Ethiopia. METHODOLOGY Data was collected fro...

  Primary non-Hodgkin lymphoma of liver is a very rare malignancy. Here we report a case of primary hepatic Burkitt’s lymphoma in a 34-year old man who was known case of acquired immunodeficiency syndrome (AIDS) and presented with weight loss, abdominal pain, and fever. Positive laboratory findings were mild anemia and elevated levels of lactate dehydrogenase (LDH) and alkaline phosphatase (AL...

Despite significant progress in treatment, chronic lymphocytic leukemia (CLL) remains an incurable disease. Advances have been made to understand the molecular pathogenesis underlying CLL progression and treatment resistance. We here review the available evidences concerning the role of the B-cell receptor (BCR) and the tumor microenvironment interactions in CLL pathogenesis. Antigen likely has...

Space occupying liver lesions usually present with abdominal pain or abnormal physical findings, such as a palpable abdominal mass or distention. Liver lesions identified in children include benign and malignant neoplasms, inflammatory masses, cysts and metastatic lesions. Two-thirds of liver lesions in children are malignant. Hepatoblastoma accounts for two-thirds of malignant liver tumors in ...