Objective To determine the capability of dynamic enhanced computed tomography (CT) to differentiate liver metastases (LMs) of well-differentiated from poorly-differentiated gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs). Methods Patients with LMs of GEP-NENs who underwent dynamic enhanced CT examination in Peking University Cancer Hospital from January 2009 to October 2015 were in...

Abstract Background Pulmonary tumor embolism is a rare entity that can arise from wide variety of neoplasms. It initially manifest as pulmonary with right heart failure and be refractory to thrombolytic therapy. Cholangiocarcinoma malignancy arises the epithelium biliary tree, representing 3% all gastrointestinal malignancies; being intrahepatic cholangiocarcinoma second most common liver after...

Recent reports by Bielschowsky (1), Harris (6), Engel and Copeland (5), Strombeck and Ekman (10), and Morris et al. (7), indicate that the genetic constitution of the rat plays a more dominant role than diet in the initiation of 2-acetylaminofluorene-induced neoplasms. While liver tumors occur in a majority of the rats and the frequency is altered somewhat by the protein content of the diet, th...

There is a wide differential diagnosis of focal liver lesions in children including inflammatory lesions, cystic lesions and benign and malignant neoplasms. Imaging confirms the presence of a focal liver lesion, assesses the extent of disease and characterises the lesion. Initial ultrasound findings will determine if other imaging modalities are required, which include nuclear medicine (NM), co...

We describe here a 67-year-old man who was diagnosed with a rare case of intraductal papillary mucinous tumors that occurred simultaneously in the liver and pancreas. Abdominal computed tomography showed a tubular and cystic dilatation of the pancreatic duct in the pancreas tail, which suggested an intraductal papillary mucinous tumor (IPMT), and multiple intrahepatic duct stones. The patient u...

Epithelioid angiomyolipoma (EAML) of liver is a rare neoplasm. Hepatic EAML is often misdiagnosed as other neoplasms such as hepatocellular carcinoma due to non-specific clinical and radiologic features. The morphologic features under microscope and immunohistochemistry staining profile are important in the diagnosis EAML. Here, we report a case of 52-year-old man who found 1.2 cm mass in liver...

A dose-response study in carcinogenesis was carried out with N-nitrosomorpholine in female F344 rats. The compound was administered in drinking water, which was supplied in controlled amounts of 20 ml per day per rat, 5 days a wk. At the two highest dose rates, 100 mg/liter and 40 mg/liter, treatment lasted 25 and 40 wk, respectively. At the other dose rates, which differed by a factor of 2.5, ...