An elderly woman presented with dyspnoea secondary to extensive mediastinal invasion by a primary well differentiated liposarcoma of the mediastinum. Five years after partial resection and postoperative radiotherapy (45 Gy) she is alive and well. To our knowledge, long term survival has not previously been reported for a non-encapsulated mediastinal liposarcoma treated by incomplete resection a...

Gastrointestinal liposarcomas are extremely rare with the most common reported morphological subtype being dedifferentiated liposarcoma and well-differentiated liposarcoma. These tumors rarely diagnosed preoperatively diagnosis is only confirmed on histopathological analysis. Treatment of gastrointestinal consists surgical excision widely negative margins followed by post-operative irradiation ...

BACKGROUND A strategy for accelerating liver regeneration after hepatectomy would offer great benefits in preventing postoperative liver failure and improving surgical outcomes. Transforming growth factor (TGF) β is a potent inhibitor of hepatocyte proliferation. Recently, thrombospondin (TSP) 1 has been identified as a negative regulator of liver regeneration by activation of local TGF-β signa...

of 2 cases and review of literature.Eur J Pediatr Surg 2001;11:1-8. 5. O’Donnell KA,Catty MG,Allen JE, Fisher JE. Lipoblastoma better termed infantile lipoma?.Pediatr Surg Int 2000;16:458-461. 6. Bolen JW, Thorning D:Benign lipoblastoma and myxoid liposarcoma: a comparitive light and electron microscopic study, Am J Surg Pathol4:163,1980. 7. Chung EB, Enzinger FM: Benign lipoblastomatosis: An a...

The treatment of patients with central liver tumors involving segments 4, 5 and 8 is a difficult clinical problem. These tumors often straddle Cantlie's line and involve parts of both lobes of the liver. The traditional management of such tumors is to perform either an extended right or an extended left hepatectomy. However, extended hepatectomies are associated with greater morbidity and morta...

We report a case of a rapidly progressing giant retroperitoneal liposarcoma weighing 22 kg in a 41-year-old Japanese man, successfully treated with surgical excision. To our knowledge, this is the largest liposarcoma in the Japanese population reported in the literature.

We report a case of metastatic liposarcoma in the bone marrow with a rapidly fatal course. In view of the poor prognosis and paucity of clinical and imaging findings in patients with high-grade liposarcoma that is metastatic to bone marrow, we propose that bone marrow examination should be performed during the patient's initial evaluation as well as follow-up examinations.

Liposarcoma is one of the most common primary neoplasms in the retroperitoneum, whereas primary mesenteric liposarcomas are rare. We encountered a case of liposarcoma which arose from the mesentery of the jejunum that was diagnosed by imaging studies before surgical operation.

HYPOTHESIS By review of a reported series, is outcome related to surveillance after hepatectomy? DESIGN We reviewed English-language literature indexed on MEDLINE from January 1, 1990, through December 31, 2002. Indexing terms were combinations of hepatectomy, colorectal metastases, and recurrence with prognostic, repeat, follow-up, or surveillance. STUDY SELECTION Studies containing any of...

BACKGROUND Dedifferentiated liposarcoma is an uncommon variant of liposarcoma, with poor prognosis and higher preponderance to local recurrence. Only nine cases of dedifferentiated liposarcoma of small bowel mesentery have been reported till now. This is a case of giant dedifferentiated liposarcoma of the small bowel mesentery, weighing nearly 9 kg (19.8 lbs), with synchronous lesions in the ex...