Pseudomonas sp. strain DF41 produces a lipopeptide, called sclerosin that inhibits the fungal pathogen Sclerotinia sclerotiorum . The aim of the current study was to deduce the chemical structure of this lipopeptide and further characterize its bioactivity. Mass spectrometry analysis determined the structure of sclerosin to be CH(3)-(CH(2))(6)-CH(OH)-CH(2)-CO-Dhb-Pro-Ala-Leu/Ile-Ala-Val-Val-D...

Isolation and screening of microorganisms from oil contaminated soil samples with biosurfactant producing ability was investigated. The biosurfactant producing ability of the microorganisms isolated from the soil samples was investigated by hemolytic assay, drop collapse test, emulsification index and methylene blue agar plate method. The best isolate was identified as Pseudomonas aeruginosa ba...

objective(s):serratia marcescens is one of the nosocomial pathogen. the ability to form biofilm is an important feature in the pathogenesis of s. marcescens. the aim of this study was to determine the anti-adhesive properties of a biosurfactant isolated from lactobacillus acidophilus atcc 4356, on s. marcescens strains. materials and methods: lactobacillus acidophilus atcc 4356, was selected as...

The present study emphasizes the diversity assessment of marine Bacillus species with special reference to biosurfactant production, respective gene expression, and discrimination among Bacillus licheniformis and Bacillus subtilis. Among the 200 individual species of eastern coastal plain of Tamil Nadu screened, five biosurfactant producing potential bacterial species with entirely different mo...

The objective of this study was to isolate and identify the chemical structure of a biosurfactant produced by Nocardia farcinica strain BN26 isolated from soil, and evaluate its in vitro antitumor activity on a panel of human cancer cell lines. Strain BN26 was found to produce glycolipid biosurfactant on n-hexadecane as the sole carbon source. The biosurfactant was purified using medium-pressur...

Biosurfactant are surface active compounds produced by microorganisms. These molecules reduce surface tension between aqueous solutions and hydrocarbon mixtures. Hundred hydrocarbon saturated soil samples were collected from thirty different areas in Chennai, TamilNadu, India. Seventy two bacterial strains were isolated and cultured by enriching carbon (Glycerol) source. Each culture medium was...

Synthetic lipopeptide analogues of the N-terminus of bacterial lipoprotein are effective activators of macrophages, neutrophils and lymphocytes. We studied the effect of the lipopeptide N-palmitoyl-S-[2,3-bis(palmitoyloxy)-(2RS)-propyl]- (R)-cysteinyl-(S)-seryl-(S)-lysyl-(S)-lysyl-(S)-lysyl-(S)-lysine [Pam3Cys-Ser-(Lys)4] on tyrosine phosphorylation in dibutyryl-cyclic-AMP-differentiated HL-60 ...

The low immunogenicity exhibited by most soluble proteins is generally due to the absence of molecular signatures that are recognized by the immune system as dangerous. In this study, we show that electrostatic binding of synthetic branched cationic or anionic lipopeptides that contain the TLR-2 agonist Pam(2)Cys markedly enhance a protein's immunogenicity. Binding of a charged lipopeptide to o...

Biosurfactant-producing microorganisms improve the efficacy of hydrocarbon biodegradation as biosurfactant is essential in making hydrocarbons available for breakdown. The present study reports isolation biosurfactant-producing bacteria that can be used crude oil remediation and to characterize generated during breakdown oil. This also evaluating synergism potentiality simultaneous power genera...

a bacterial strain (designated as alcaligenes sp. ms-103) isolated from oil sample of the aghajari oilfield in the south of iran, was able to produce an effective extracellular lipopolysaccharide biosurfactant (1.2±0.05 g/l) on molasses as a sole carbon source. the highest surface tension reduction to level 20 mn/m was achieved by biosurfactant produced by cells grown on molasses under optimum ...