BACKGROUND Epidemiologic studies demonstrate a relation between preeclampsia and an increased risk of future maternal coronary heart disease. The pathophysiology of the underlying mechanism is unknown. Disorders of lipoprotein metabolism may contribute to endothelial dysfunction. Oxidative stress and decreased antioxidant defense enhances free radical-mediated membrane lipid peroxidation and po...

A deficit in glucose uptake and a deposition of amyloid beta-peptide (A beta) each occur in vulnerable brain regions in Alzheimer's disease (AD). It is not known whether mechanistic links exist between A beta deposition and impaired glucose transport. We now report that A beta impairs glucose transport in cultured rat hippocampal and cortical neurons by a mechanism involving membrane lipid pero...

introduction: in the present investigation, we aimed to study the effect of different concentrations of ascorbate/vitamin c, on membrane integrity, viability, and acrosome reaction of human spermatozoa in presence of ferrous (fe2+) ions as lipid peroxidation (lpo) promoter. material and methods: we used 12 semen samples from healthy donors in shahrekord. the samples were then washed twice with ...

Hyperglycemia is the most important contributor in the onset and progress of diabetic complications mainly by producing oxidative stress. The present study was carried out to observe, the antihyperglycemic effect of sodium orthovanadate (SOV) and Trigonella foenum graecum seed powder (TSP) administration on blood glucose and insulin levels, membrane linked enzymes (monoamine oxidase, acetylchol...

Milk contains bioactive molecules with important functions as defensive proteins; among them are the whey protein lactoferrin and proteins of milk fat globule membrane (MFGM) present in buttermilk. The aim this study has been to investigate effects lactoferrin, whey, buttermilk modulators intestinal innate immunity oxidative stress on epithelial cells, evaluate its potential use for development...

Low concentrations of calcium ions (Ca2+) are maintained in living cells by the Ca-ATPase calcium pump of the plasma membrane. The presence of a calcium pump in corals has been confirmed and its temperature related breakdown underlies coral bleaching. There is also mounting evidence from stable calcium isotope ratios in the skeleton for involvement of a calcium pump in coral calcification. Hydr...

this study was designed to explore the protective effects of ascorbic acid and water extract of spirulina platensis (blue green algae) on methotrexate-induced lipid peroxidation using goat liver as the lipid source. this in vitro evaluation was done by measuring the malondialdehyde, 4-hydroxy-2-nonenal, reduced glutathione and nitric oxide content of tissue homogenates. the study reveals the li...

plant growth is often limited by low levels of soil micronutrients such as copper (cu), ‎especially in calcareous salt-affected soils of arid and semiarid regions. the aim of this ‎work was to investigate individual and combined effects of salinity and cu on growth, leaf ‎relative water content (lrwc), cell membrane permeability, lipid peroxidation, and total ‎phenolic content (tpc) of rosemary...

background: diabetes mellitus is associated with chronic changes in peripheral arteries because of oxidative stress and insufficient antioxidative defense mechanism. omega-3 fatty acid supplementation could be effective in some diabetes complications; however, polyunsaturated fatty acids may increase lipid peroxidation. this study aimed to determine whether eicosapentaenoic acid alone or in con...

Silybum marianum is an important medicinal plant with high antioxidant properties. Static magnetic field (SMF) is a kind of abiotic stresses which can affect growth and antioxidant capacity of medicinal plants. In this research, the effects of SMF on total phenolic and flavonoid contents, radical scavenging activity, and anatomical alterations were investigated in S. marianum seedlings. Five-da...