Customized patient instrumentation (CPI) combines preoperative planning with customized cutting jigs to position and align implants during total knee arthroplasty (TKA). We compared postoperative implant alignment of patients undergoing surgery with CPI to traditional TKA instrumentation for accuracy of implant placement. Twenty-five consecutive TKAs using CPI were analyzed. Preoperative CT sca...

Hyperpronation may cause malalignment of the lower extremity, frequently leading to structural and functional deficits both in standing and walking. Our aim was to study the effect of induced foot hyperpronation on pelvic and lower limb alignment while standing. Thirty-five healthy subjects were requested to remain in a natural standing position for 20s in four different modes: feet flat on the...

STUDY DESIGN In vivo biomechanical study using a three-dimensional (3D) musculoskeletal model for elderly individuals with or without pelvic retroversion. PURPOSE To evaluate the effect of pelvic retroversion on the sagittal alignment of the spine, pelvis, and lower limb in elderly females while standing and walking. OVERVIEW OF LITERATURE Patients with hip-spine syndrome have concurrent hi...

UNLABELLED The objective of this study was to verify self-care guidelines together with lower limb home exercises alter ankle and foot plantar pressure and alignment in patient with Type 2 Diabetes Mellitus (DM) measuring health and sociodemographic factors. The health factors analyzed were sensitivity and circulation aspects, risk rating, and neuropathy symptom score, ankle and foot alignment ...

BACKGROUND Dynamic alignment of "knee-in & toe-out" is a risk factor for anterior cruciate ligament injury and is possibly influenced by static knee alignment, range of tibial rotation and tibial plateau geometry. METHODS Twenty-eight healthy women were classified into valgus, neutral and varus groups based on static alignment of their knees. A 3-dimensional motion analysis was carried out fo...

Background There is an ongoing debate whether patients with constitutional varus should be restored to neutral mechanical alignment following total knee arthroplasty (TKA). Objective The aim of this retrospective cohort study is to determine whether mild unintentional postoperative varus alignment (3°-6°) influences TKA outcome in patients with and without preoperative varus alignment due to ...

Vertebrate Hoxd genes are essential determinants of limb morphogenesis. In order to understand the genetic control of their complex expression patterns, we have used a combined approach involving interspecies sequence alignments in parallel with transgenic analyses, followed by in vivo mutagenesis. Here, we report on the identification of a regulatory element that is located in the vicinity of ...

This study describes a new calibration procedure that provides simple and accurate method to place align an inertial measurement unit (IMU) sensor with the relative clinical bone frame on developed lower limb skeletal model. The can be easily replicated without need for additional tools and, more importantly, it is independent of joint attachment position. proposed was validated under realistic...