نتایج جستجو برای: lf

تعداد نتایج: 6627  

2016
Nada Zemankova Katarina Chlebova Jan Matiasovic Jana Prodelalova Jan Gebauer Martin Faldyna

BACKGROUND Lactoferrin (LF) is an 80 kDa glycoprotein which is known for its effects against bacteria, viruses and other pathogens. It also has a high potential in nutrition therapy and welfare of people and a variety of animals, including piglets. The ability to bind lipopolysaccharide (LPS) is one of the described anti-inflammatory mechanisms of LF. Previous studies suggested that cells can b...

Journal: :Circulation 1998
R L Cooley N Montano C Cogliati P van de Borne W Richenbacher R Oren V K Somers

BACKGROUND Short-term variability of RR interval and blood pressure occurs predominantly at low frequency (LF; approximately 0.1 Hz) and high frequency (approximately 0.25 Hz). The arterial baroreflex is thought to be the predominant determinant of the LF component of RR variability. Patients with severe congestive heart failure (CHF) have an attenuated or absent LF oscillation in RR variabilit...

2014
Jeffrey G. Shaffer Donald S. Grant John S. Schieffelin Matt L. Boisen Augustine Goba Jessica N. Hartnett Danielle C. Levy Rachael E. Yenni Lina M. Moses Mohammed Fullah Mambo Momoh Mbalu Fonnie Richard Fonnie Lansana Kanneh Veronica J. Koroma Kandeh Kargbo Darin Ottomassathien Ivana J. Muncy Abigail B. Jones Megan M. Illick Peter C. Kulakosky Allyson M. Haislip Christopher M. Bishop Deborah H. Elliot Bethany L. Brown Hu Zhu Kathryn M. Hastie Kristian G. Andersen Stephen K. Gire Shervin Tabrizi Ridhi Tariyal Mathew Stremlau Alex Matschiner Darryl B. Sampey Jennifer S. Spence Robert W. Cross Joan B. Geisbert Onikepe A. Folarin Christian T. Happi Kelly R. Pitts F. Jon Geske Thomas W. Geisbert Erica Ollmann Saphire James E. Robinson Russell B. Wilson Pardis C. Sabeti Lee A. Henderson S. Humarr Khan Daniel G. Bausch Luis M. Branco Robert F. Garry

BACKGROUND Lassa fever (LF), an often-fatal hemorrhagic disease caused by Lassa virus (LASV), is a major public health threat in West Africa. When the violent civil conflict in Sierra Leone (1991 to 2002) ended, an international consortium assisted in restoration of the LF program at Kenema Government Hospital (KGH) in an area with the world's highest incidence of the disease. METHODOLOGY/PRI...

Introduction: Labyrinthine fistulae (LF) are the common complications of chronic otitis media (COM) of squamosal variety. The final therapeutic outcome of this condition is to preserve the cochlear and vestibular functions. Herein, we present the data of the cases managed at our institute with respect to their presenting complaints, adopted therapeutic approaches and outcomes.  <br ...

Journal: :American journal of physiology. Heart and circulatory physiology 2003
C C Liu Terry B J Kuo Cheryl C H Yang

Our previous studies demonstrated that premenopausal women have dominant vagal and subordinate sympathetic activity compared with age-matched men. This study was designed to investigate the role of estrogen in gender-related autonomic differences. We evaluated the heart rate variability of four healthy groups: age-matched postmenopausal women without hormone replacement therapy (PM), postmenopa...

2017
Ece Kilic Marina V. Novoselova Su Hui Lim Nikolay A. Pyataev Sergey I. Pinyaev Oleg A. Kulikov Olga A. Sindeeva Oksana A. Mayorova Regan Murney Maria N. Antipina Brendan Haigh Gleb B. Sukhorukov Maxim V. Kiryukhin

Lactoferrin (Lf) has considerable potential as a functional ingredient in food, cosmetic and pharmaceutical applications. However, the bioavailability of Lf is limited as it is susceptible to digestive enzymes in gastrointestinal tract. The shells comprising alternate layers of bovine serum albumin (BSA) and tannic acid (TA) were tested as Lf encapsulation system for oral administration. Lf abs...

Journal: :The Journal of biological chemistry 2004
Xudong Liang John J Young Sherrie A Boone David S Waugh Nicholas S Duesbery

Anthrax lethal factor (LF) is a Zn2+ -metalloprotease that cleaves and inactivates mitogen-activated protein kinase kinases (MEKs). We have used site-directed mutagenesis to identify a cluster of residues in domain II of LF that lie outside the active site and are required for cellular proteolytic activity toward MEKs. Alanine substituted for Leu293, Lys294, Leu514, Asn516, or Arg491 caused a 1...

1998
George C. Necula Peter Lee

This paper presents a logical framework derived from the Edinburgh Logical Framework (LF) 5] that can be used to obtain compact representations of proofs and eecient proof checkers. These are essential ingredients of any application that manipulates proofs as rst-class objects, such as a Proof-Carrying Code 11] system, in which proofs are used to allow the easy validation of properties of safet...

Journal: :International journal of pharmaceutics 2015
Yung-Chih Kuo Yu-Chun Chen

Lactoferrin (Lf) and folic acid (FA) were crosslinked on poly(lactide-co-glycolide) (PLGA) nanoparticles (NPs) for transporting etoposide across the blood-brain barrier (BBB) and treating human brain malignant glioblastoma. Lf- and FA-grafted PLGA NPs (Lf/FA/PLGA NPs) were employed to permeate the monolayer of human brain-microvascular endothelial cells (HBMECs) regulated by human astrocytes an...

2013
Sarah K Nanyonga Andy R Opoku Francis B Lewu Opeoluwa O Oyedeji Moganavelli Singh Adebola O Oyedeji

Purpose: To investigate the antioxidant potential and cytotoxicity of the leaf and bark extracts of Tarchonanathus campharatus.. Methods: The antioxidant activity of the aqueous leaf extract (Aq LF), methanol leaf extract (MET LF), dichloromethane leaf extract (DCM LF), methanol bark extract (MET BK), dichloromethane bark extract (DCM BK), and ethyl acetate bark extract (Et Ac BK) were examined...

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