نتایج جستجو برای: leukocyte telomere length

تعداد نتایج: 346584  

2016
Shahinaz M. Gadalla Payal P. Khincha Hormuzd A. Katki Neelam Giri Jason Y. Y. Wong Stephen Spellman Jack A. Yanovski Joan C. Han Immaculata De Vivo Blanche P. Alter Sharon A. Savage

BACKGROUND Telomere length <1st percentile-for-age in leukocyte subsets by flow cytometry with fluorescence in situ hybridization (flow FISH) is highly sensitive and specific in diagnosing patients with dyskeratosis congenita (DC), a telomere biology disorder. METHODS We evaluated the clinical utility of the high-throughput quantitative real-time PCR (qPCR) relative telomere length (RTL) meas...

Journal: :Clinical nutrition 2015
Sonia García-Calzón Adriana Moleres Miguel A Martínez-González J Alfredo Martínez Guillermo Zalba Amelia Marti

BACKGROUND & AIMS Oxidative stress and inflammation seem to be potential underlying mechanisms for telomere attrition. A lack of specific antioxidants is believed to increase free radical damage and a greater risk for telomere shortening. Our aim was to evaluate the relationship between diet and leukocyte telomere length in a cross-sectional study of children and adolescents. We hypothesized th...

Journal: :American Journal of Respiratory and Critical Care Medicine 2014

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