نتایج جستجو برای: leukoaraiosis

تعداد نتایج: 714  

Journal: :Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2012
Bruce C V Campbell Archana Purushotham Soren Christensen Patricia M Desmond Yoshinari Nagakane Mark W Parsons Maarten G Lansberg Michael Mlynash Matus Straka Deidre A De Silva Jean-Marc Olivot Roland Bammer Gregory W Albers Geoffrey A Donnan Stephen M Davis

Diffusion-weighted imaging (DWI) is commonly used to assess irreversibly infarcted tissue but its accuracy is challenged by reports of diffusion lesion reversal (DLR). We investigated the frequency and implications for mismatch classification of DLR using imaging from the EPITHET (Echoplanar Imaging Thrombolytic Evaluation Trial) and DEFUSE (Diffusion and Perfusion Imaging Evaluation for Unders...

Journal: :JAMA neurology 2014
Melinda S Burnett Robert J Witte J Eric Ahlskog

IMPORTANCE Markedly enlarged Virchow-Robin spaces throughout the striatum appear occasionally on magnetic resonance imaging (MRI) scans of the elderly, and this type of striatum is known as the Swiss cheese striatum (SCS); however, its clinical impact is unknown. OBJECTIVE To determine the clinical features associated with SCS detected on MRI scans. DESIGN, SETTING, AND PARTICIPANTS A blind...

Journal: :Acta neurologica Taiwanica 2011
Chia-Chen Chang Wen-Neng Chang Chi-Ren Huang Chia-Wei Liou Tsu-Kung Lin Chen-Hsien Lu

PURPOSE Dizziness/vertigo are important public heath care issues especially in elderly patients. Isolated dizziness/vertigo without neurological deficits has seldom been considered a symptom/sign due to vascular origin. Recently, some studies have suggested that vascular origin should be considered in cases of positional vertigo and isolated vertigo or dizziness when the etiology remains unclea...

Journal: :Anesthesiology 2014
Catherine C Price Jared J Tanner Ilona Schmalfuss Cynthia Wilson Garvan Peter Gearen David Dickey Kenneth Heilman David L McDonagh David J Libon Christiana Leonard Dawn Bowers Terri G Monk

BACKGROUND Total knee arthroplasty improves quality of life but is associated with postoperative cognitive dysfunction in older adults. This prospective longitudinal pilot study with a parallel control group tested the hypotheses that (1) nondemented adults would exhibit primary memory and executive difficulties after total knee arthroplasty, and (2) reduced preoperative hippocampus/entorhinal ...

Journal: :Journal of neuropathology and experimental neurology 2014
Leslie R Bridges Joycelyn Andoh Andrew J Lawrence Cheryl H L Khoong Wayne Poon Margaret M Esiri Hugh S Markus Atticus H Hainsworth

The blood-brain barrier protects brain tissue from potentially harmful plasma components. Small vessel disease (SVD; also termed arteriolosclerosis) is common in the brains of older people and is associated with lacunar infarcts, leukoaraiosis, and vascular dementia. To determine whether plasma extravasation is associated with SVD, we immunolabeled the plasma proteins fibrinogen and immunoglobu...

Journal: :Stroke 2002
Leonardo Pantoni Michela Simoni Giovanni Pracucci Reinhold Schmidt Frederik Barkhof Domenico Inzitari

BACKGROUND AND PURPOSE It has been hypothesized that the use of different visual rating scales partly explains the discordant results of studies investigating risk factors and clinical correlates of age-related cerebral white matter changes (leukoaraiosis). We aimed to compare 6 widely used rating scales for leukoaraiosis and to calculate conversion coefficients of the score of 1 scale in the s...

Journal: :AJNR. American journal of neuroradiology 2008
C Ryberg E Rostrup K Sjöstrand O B Paulson F Barkhof P Scheltens E C W van Straaten F Fazekas R Schmidt T Erkinjuntti L-O Wahlund A M Basile L Pantoni D Inzitari G Waldemar

BACKGROUND AND PURPOSE The corpus callosum (CC) is the most important structure involved in the transmission of interhemispheric information. The aim of this study was to investigate the potential correlation between regional age-related white matter changes (ARWMC) and atrophy of CC in elderly subjects. MATERIALS AND METHODS In 578 subjects with ARWMC from the Leukoaraiosis And DISability (L...

Journal: :Stroke 2014
A-Hyun Cho Yong-Pil Cho Deok Hee Lee Tae-Won Kwon Sun U Kwon Dae-Chul Suh Jong S Kim Dong-Wha Kang

BACKGROUND AND PURPOSE Reperfusion injury can be revealed as delayed gadolinium enhancement in the subarachnoid space on a fluid-attenuated inversion recovery image, which is designated as a hyperintense acute reperfusion marker (HARM). We sought to investigate the occurrence and predictors of HARM and its association with new ischemic infarcts after carotid revascularization. METHODS Forty-f...

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