Patients with chronic granulocytic leukaemia (CGL) have increased numbers of granulocyte colony-forming cells (CFC) in the peripheral blood. I When the disease is controlled by chemotherapy, leucapheresis, or irradiation circulating CFC fall to low levels.2 Since irradiation in vitro impairs granulocyte colony growth3 the therapeutic effect of splenic irradiation is presumably related to CFC da...

111Indium autologous mixed leucocyte scanning has recently been used for the investigation of Crohn's disease. Nineteen patients had indium scans to assess disease extent and activity. The scans were compared with conventional imaging techniques and indices of disease activity including clinical scores, ESR, CRP, and GI protein loss. In five patients with active disease the scans were negative ...

Vascular endothelial cells play a pivotal role in regulating leucocyte recruitment during inflammation, and their responses can be modulated by their local environment, including cells of the tissue stroma. We have developed a model system to examine how the communication between endothelial cells and fibroblasts regulates the recruitment of leucocytes and their subsequent subendothelial fate. ...

1. In sixteen patients with severe chronic renal failure the rate constant for total sodium efflux from leucocytes was significantly reduced compared with that in thirty control subjects. This difference lay chiefly in the glycoside-sensitive ('active') moiety of sodium efflux. 2. In sixteen patients receiving regular haemodialysis, the rate constant for total sodium efflux from the leucocyte w...

Xanthou, M. (1972). Archives of Disease in Childhood, 47, 741. Leucocyte blood picture in ill newborn babies. Serial blood leucocyte counts were made on 35 ill preterm and term babies during the first 28 days of life. Ill babies with no clinical or bacteriological evidence of infection showed no changes in the blood leucocytes during the neonatal period when compared with normal babies. The cha...

In many medical applications, computer vision is required to step behind the image preprocessing level and perform recognition tasks without human interaction. We focused our work on blood tests for leucocyte detection and counting. This test is generally performed manually and required for infection diagnosis. We developed a method for cells classification and counting using images from a labo...