in the present study, the toxic effects on the embryos and larvae of the turbot were used as a model to investigate the diazinon, which contaminates aquatic ecosystems. the number of dead embryos significantly increased in response to diazinon concentrations 0.2, 0.4, 0.8, 1.6, 3.2, and 7.4 mg/l. the 48h lc50 value of diazinon for turbot embryos was estimated at 1.85 mg/l. dose–response decreas...

BACKGROUND Programmed cell death or apoptosis is an essential process for tissue homeostasis. Hepatocyte apoptosis is a common mechanism to many forms of liver disease. This study was undertaken to test the role of ILK in hepatocyte survival and response to injury using a Jo-2-induced apoptosis model. METHODS For survival experiments, ILK KO and WT mice received a single intraperitoneal injec...

Tench, Tinca tinca, were exposed to three treatments (one acute lethal 96 hrs Lc50/48 hrs and two chronic sublethal 10 and 25% Lc50/504 hrs) each of Mercury, Cadmium and Lead and its behaviour as an indicator of impaired hematology was studied. It was observed that impairments in hematological parameters (increased/decreased Hct, Hb, RBC, WBC and Lct) were reflected in behaviour of fish in the ...

Tench, Tinca tinca, were exposed to three treatments (one acute lethal 96 hrs Lc50/48 hrs and two chronic sublethal 10 and 25% Lc50/504 hrs) each of Mercury, Cadmium and Lead and its behaviour as an indicator of impaired hematology was studied. It was observed that impairments in hematological parameters (increased/decreased Hct, Hb, RBC, WBC and Lct) were reflected in behaviour of fish in the ...

INTRODUCTION Aedes aegypti is responsible for the transmission of the dengue and yellow fever viruses. This study evaluated the effects of extracts from Cnidosculos phyllacanthus, Ricinus communis, and Coutarea hexandra on the developmental periods of A.aegypti larvae and pupae. Crude extracts of C. phyllacanthus and C. hexandra and oil from R. communis and C. phyllacanthus were used. METHODS...

Bombus terrestris bumblebees are important pollinators of wild flowers, and in modern agriculture they are used to guarantee pollination of vegetables and fruits. In the field it is likely that worker bees are exposed to pesticides during foraging. To date, several tests exist to assess lethal and sublethal side-effects of pesticides on bee survival, growth/development and reproduction. Within ...

widespread use of nanosilver can be led the contamination of aquatic environment and impact on living organisms such as fishes. we investigated histopathological changes in the gills tissue of caspian roach fingerlings after two weeks exposure to sublethal concentrations of nanosilver. following one and two weeks exposure, necrosis, shortening of secondary lamellae, edema, destruction of epithe...

BACKGROUND Ischemia-reperfusion (I/R) is the main cause of acute kidney injury (AKI) in patients. We investigated renal microRNA (miRNA) expression profiles and the time course of changes in selected miRNA expressions after renal I/R to characterize the miRNA network activated during development and recovery from AKI. METHODS AND RESULTS One day after lethal (30 minutes) and sublethal (20 min...