BACKGROUND The coadministration of prednisone and ultralow-dose aspirin has been recommended for the management of various diseases, but the safety of this combination in dogs has not been studied. HYPOTHESES The gastroduodenal lesions associated with prednisone and ultralow-dose aspirin administration will be similar to those caused by prednisone alone, but both treatments will result in mor...

Background: Health-related quality of life evaluation is scarce in patients with molluscum contagiosum (MC) & little known about the meaningfulness lesion count reduction. Methods: B-SIMPLE1,2 4 Phase 3 trials evaluated safety efficacy once-daily application berdazimer gel 10.3% or vehicle for 12 weeks MC. Children’s Dermatology Life Quality Index (cDLQI) questionnaires were collected from B-SI...

BACKGROUND AND OBJECTIVE A minimally invasive fractional radiofrequency microneedle (FRM) device has been used in skin rejuvenation and acne scars, and a recent pilot study demonstrated the positive therapeutic effect on acne. We evaluated the efficacy of FRM device for acne vulgaris in Asians and conducted objective measurement to assess its effect on sebum production. PATIENTS AND METHODS T...

BACKGROUND AND PURPOSE Previous studies have suggested that patients' potential for poststroke language recovery is related to lesion size; however, lesion location may also be of importance, particularly when fiber tracts that are critical to the sensorimotor mapping of sounds for articulation (eg, the arcuate fasciculus) have been damaged. In this study, we tested the hypothesis that lesion l...

Background Semi-quantitative magnetic resonance imaging (MRI) scoring is more challenging in some anatomic regions than others. Bone marrow lesion (BML) an important feature and may be closely related to clinical outcomes arthritis The Knee Inflammation MRI Scoring System (KIMRISS) scores BML synovitis-effusion from fluid-sensitive sagittal [1] . Via web-based interface, readers place ready-mad...

introduction: the claustrum interconnects with the allocortical and neocortical regions and also projects to the hippocampus and the amygdala. .the role of claustrum in the complex partial seizure is not clear. thus in this study the effect of amygdala lesion on anterior claustrum kindled seizures in rat were investigated. methods: male wistar rats, weighting 250-300 g, were received dc current...

purpose: to report a rare malignant melanoma with chalazion-like presentation.  case report: a 36-year old woman with a chalazion-like mass in the left upper lid, having been resected twice, was referred to our center for the management of recurrence. the total resection of the suspicious area was done. histopathologic examination confirmed the diagnosis of malignant melanoma. the appropriate r...

aim : the purpose of this study was to assess the incidence of 16bp insertion of intron 3 p53 in gastritis lesion and its correlation with clinicopathological aspects. background : p53 alterations have been implicated in the development of gastric malignancies. patients and methods : 97 gastritis and normal adjacent tissues were investigated for p53 gene analysis using pcr-sequencing of intron3...

background: limited data available about the mechanisms of dysphagia and areas involving swallow after brain damage; accordingly it is hard to predict which cases are more likely to develop swallowing dysfunction based on the neuroimaging. the aim of this study was to investigate the relationship between brain lesions and dysphagia in a sample of acute conscious stroke patients. materials and m...