Development in ART has been remarkable in the last decades. Several medical conditions affecting the male fertility status are now treated by ART, especially by the combination of in vitro fertilization and intracytoplasmic sperm injection. ICSI is now the treatment of choice of most untreatable causes of male infertility, including immunologic infertility, severe oligozoospermia and azoospermi...

objective: melatonin, the chief secretory product of the pineal gland, regulates dynamic physiological adaptations that occur in seasonally breeding mammals as a response to changes in daylight hours. because of the presence of melatonin in semen and the membrane melatonin receptor in spermatozoa, the impact of melatonin on the regulation of male infertility is still questionable. the aim of th...

Background: Seminal plasma of mammals is a complex fluid, which serves as a carrier for the spermatozoa on their journey from the male testes to their target, the oocyte. Seminal plasma contains a variety of biochemical components, some of which are relatively specific for the regulation of sperm function. The objective of this study was to investigate enzyme activities aspartate-amino-transfer...

Evaluation and surgical treatment of male infertility has evolved and expanded, now leading to more precise diagnoses and tailored treatments with diminished morbidity and greater success. Surgeries for male infertility are divided into four major categories: (i) diagnostic surgery; (ii) surgery to improve sperm production; (iii) surgery to improve sperm delivery; and (iv) surgery to retrieve s...

OBJECTIVE To determine whether particular semen characteristics in various clinical diagnoses of infertility are associated with high oxidative stress and whether any group of infertile men is more likely to have high seminal oxidative stress. Reactive oxygen species (ROS) play an important role in sperm physiological functions, but elevated levels of ROS or oxidative stress are related to male...

background: leptin and its receptor are present in spermatozoa; however, the role of leptin in sperm function is still controversial. our present study aimed at demonstrating the effect of cryopreservation on sperm dna fragmentation (dnaf) and investigating the possible effects of sperm capacitation techniques and leptin in vitro incubation on frozen-thawed sperm dnaf and oxidative stress. meth...

The present study evaluated the relationship between Bali bull (Bos javanicus) seminal plasma proteins and different semen quality parameters. Semen samples from 10 mature Bali bulls were evaluated for conventional semen parameters (general motility, viability, and normal morphology), sperm functionality (acrosome reaction, sperm penetration rate, sperm penetration index), sperm kinetics (compu...

Dr. Sandro Esteves and collegues, from Brazil, performed on page xx at this issue of the International Braz J Urol an elegant review that discuss how the new World Health Organization (WHO) criteria for seminal parameters could affect the clinical management of men presenting with male infertility. The authors emphasized the factors that limit the use of seminal parameters as a surrogate for ma...

Short-term storage of fish sperm is a simple and cost-effective process in fishery research from basic to applied perspectives. It has been used elucidate evaluate gamete biology quality, perform vitro fertilization, develop cryopreservation. Sperm short-term selective breeding, hatchery production advanced molecular investigations such as disease detection commercial species aquaculture well b...

Sperm DNA damage is recognized as an important biomarker of male infertility. To investigate this, sperm DNA damage was assessed by the sperm chromatin dispersion (SCD) test in semen and motile spermatozoa harvested by combined density gradient centrifugation (DGC) and swim-up in 161 couples undergoing in vitro fertilization (IVF). Semen analysis and sperm DNA damage results were compared betwe...