spirometry has been used as a common diagnostic test in asthma. most of the patients with a mild asthma have a fev1 within normal range. hence, other diagnostic methods are usually used. the aim of this study was to evaluate whether eosinophil cationic protein (ecp) could be an accurate diagnostic marker of mild asthma. in this study diagnosis of asthma was made according to internationally acc...

erythraeus (zaracarus) coleopterus mortazavi, hajiqanbar & saboori, 2012 (acari: parasitengona: erythraeidae) was described based on a single specimen from kerman province, southeastern iran, associated with a scarabaeid beetle, cyphonoxia sp. (coleoptera: scarabaeidae). this species reports for the second time from stored grain (off host) in saqqez and baneh cities, kurdistan province, western...

Asthma is frequently characterized by eosinophil-rich airway inflammation. Airway eosinophilia is associated with asthma exacerbations and likely plays a part in airway remodeling. Eosinophil recruitment from the bloodstream depends on circulating eosinophils becoming activated, which leads to eosinophil arrest on activated endothelium, extravasation, and continued movement through the bronchia...

respiratory virus infection is a major cause of asthma exacerbation. however, the underlying mechanisms of  this exacerbation  are unknown. therefore,  to  determine  the mechanisms, we examined the effect of influenza infection in a murine model of asthma.mice were divided into four groups: the phosphate-buffered saline (pbs), house dust mite (hdm), influenza, and hdm/influenza groups. the inf...

Dynamic gene expression is a major regulatory mechanism that directs hematopoietic cell fate and differentiation, including eosinophil lineage commitment and eosinophil differentiation. Though GATA-1 is well established as a critical transcription factor (TF) for eosinophil development, delineating the transcriptional networks that regulate eosinophil development at homeostasis and in inflammat...

A case of larva migrans or serpiginous linear dermatitis on the scalp of a teenager is reported. An ancylostomid larva was found within a sebaceous gland acinus. The unusual skin site for larva migrans as well as the penetration through the sebaceous gland are highlighted. The probable mechanism by which the parasite reached the skin adnexa is discussed.