One of the main challenges of the Tevatron at Fermilab and the Large Hadron Collider (LHC) at CERN is the determination of Standard Model (SM) parameters at the TeV scale. In this context various processes will be investigated which involve bottom-quark jets in the final state, for example decays of top-quarks or gauge bosons of the weak interaction. Hence the theoretical understanding of proce...

Tumour growth and expansion are the result of proliferative activity and the capacity to eliminate cells by apoptosis and/or necrosis. The present study was aimed at comparing the apoptosis and proliferation intensity in cells of adenocarcinomas of the large intestine with the expression of metallothionein (MT), the grade of the tumour and the depth to which the tumour infiltrated the intestina...

Diffuse large B-cell lymphoma (DLBCL) is one of the most common yet aggressive types and remains incurable in 40% patients. Herein, we profiled transcriptomes 94,324 cells from 17 DLBCLs 3 control samples using single-cell RNA-sequencing technology, creating a comprehensive map for tumor infiltrating immune DLBCL. High degrees inter- intratumor heterogeneity were revealed, identified 73 gene ex...

  A male patient with acute renal failure (ARF) due to large B-cell non-Hodgkin lymphoma infiltration of kidney is presented. The diagnosis was suspected because of coincidence of ARF and tumor lysis syndrome non-responsive to conservative renal therapies. A renal biopsy confirmed diagnosis and appropriate chemotherapy led to complete improvement of renal function.  

Background: Screening and counselling is the most effective way to prevent the birth of children with thalassemia major. An accurate and relatively less time-consuming protocol is necessary to screen large populations. Separating iron deficiency anaemia from thalassemia trait based on blood cell parameters has been used by hematologists for many years. We aimed to design a new approach to scree...

background: mature t/ nk-cell neoplasms are a rare group of disorders and their presentation as leukemia is even rarer. most of the previous studies have focused on mature b-cell lineage leukemias and there is a paucity of data on mature t/nk-cell lineage leukemias. we, therefore, planned this study to analyze their spectrum, frequency, morphology and immunophenotypic features. methods: all cas...

clinical studies have shown that in pathological conditions such as endometriosis and reproductive tract infection (male and female) there is an activation status of macrophages that produce large quantities of nitric oxide (no) in addition to other effector molecules. large amounts of no may have embryotoxic roles and produce infertility. this study was designed to evaluate the effect of diffe...

This paper presents a new mathematical model for integrated dynamic cellular manufacturing systems and production planning that minimizes machine purchasing, intra-cell material handling, cell reconfiguration and setup costs. The presented model forms the manufacturing cells and determines the quantity of machine and movements  during each period of time. This problem is NP-hard, so a meta-heur...