Title:Changes in fibroblast growth factor 23 levels in normophosphatemic patients with chronic kidney disease stage 3 treated with lanthanum carbonate: results of the PREFECT study, a phase 2a, double blind, randomized, placebo-controlled trial

Investigations were conducted on a series of calcium and lanthanum oxides catalyst for biodiesel production. Mixed oxides catalyst showed a superior transesterification activity over pure calcium or pure lanthanum oxide catalysts. The catalyst activity was correlated with surface basicity and specific surface areas. The effects of water and free fatty acids (FFA) levels in oil feedstock, water ...

2 Abstract Apatite-type lanthanum silicates/germanates have been attracting considerable interest as a new class of oxide ion conductors, whose conductivity is mediated by oxide ion interstititials. For the germanates, it has been shown that, depending on composition, the cell can be either hexagonal or triclinic, with evidence for reduced low temperature conductivities for the latter, attribut...

BACKGROUND Currently there is a lack of effective treatment options for patients with calciphylaxis. There is anecdotal evidence that non-calcium based phosphorus binders may offer some benefit. The aim of this pilot study is to determine if lanthanum carbonate is effective in inducing remission of calciphylaxis lesions and demonstrate an improved DLQI (Dermatology Life Quality Index). METHOD...

Highly water-soluble lanthanum and cerium citrates or malates with ethylenediaminetetraacetate (NH(4))(8)[Ln(2)(Hcit)(2)(EDTA)(2)]·9H(2)O [Ln = La, 1; Ce, 2], K(8)[La(2)(Hcit)(2)(EDTA)(2)]·16H(2)O (3) and K(6)[Ln(2)(Hmal)(2)(EDTA)(2)]·14H(2)O [Ln = La, 4; Ce, 5] (H(4)cit = citric acid, H(3)mal = malic acid, and H(4)EDTA = ethylenediaminetetracetic acid) were prepared from the reactions of lanth...

Ruthenium red and colloidal lanthanum were used to determine the site of the structural barriers to diffusion within the intercellular spaces of frog skin epithelium. Electron micrographs show that occluding zonules located at the outer border of the stratum corneum and at the outer layer of the stratum granulosum are true tight junctions since they are impermeable to these tracers. Measurement...

Asthmatics are known to react to inhaled hyperosmolar solution. Therefore, the effect of hyperosmolar salt solutions on tight junctions of the airway epithelium was investigated by electron microscopy. Rat trachea was perfused with different concentrations of sodium chloride (NaCl) and then fixed from the luminal side with glutaraldehyde to which the electron dense tracer lanthanum chloride had...

Past studies have shown that the epithelial lining of the epididymis in adult mice deficient in protective protein cathepsin A (PPCA -/-) becomes swollen and vacuolated as a result of an accumulation of pale lysosomes, some very large, in addition to the presence of an abundance of macrophages infiltrating the intertubular spaces. The purpose of this study was to assess the integrity of the epi...

The influence of polyvalent cations on the activation of end plate receptors has been studied in vitro on the sartorius muscle of the frog. In the absence of extracellular calcium, the sensitivity of the receptors to depolarizing quaternary ammonium salts was markedly reduced. Maximum receptor activation occurred in those fibers equilibrated in 1.8 m calcium Ringer solution, with the response b...

BACKGROUND High levels of fibroblast growth factor 23 (FGF23) are associated with mortality and progression of chronic kidney disease (CKD). Reducing dietary phosphorus intake lowers FGF23 secretion in healthly individuals, but there is little data on its effects in patients with pre-dialysis CKD. METHODS Using a 2×2 factorial design, we randomly assigned 16 normophosphataemic CKD stage 3-4 p...