نتایج جستجو برای: langerhans histiocytosis

تعداد نتایج: 12631  

Introduction:Langerhans cell histiocytosis (LCH) refers to a group of rare reticuloendothelial system disorders and it occurs most often in young adults and children. A 57-year-old edentulous female patient who complained of dull pain in the posterior region of the mandible referred to the dental office, with a complaint of dull pain in the posterior region of the mandible. The lesion was diagn...

Journal: :Blood 2013
Mark L Heaney

In this issue of Blood, Haroche and colleagues report significant therapeutic activity of the BRAF inhibitor, vemurafenib, in 3 patients with rare histiocytic conditions, Erdheim-Chester disease and Langerhans cell histiocytosis.

Journal: :Internal medicine 2015
Wei Luo Ya-lun Li Lian Jia Chun-tao Liu

We herein report an extremely rare case of pulmonary Langerhans cell histiocytosis with a solitary enlarged inguinal lymph node. A 19-year-old man presented with a non-productive cough lasting for over a five-month period and an enlarged left inguinal lymph node that had persisted for four months. A histopathological study of the lymph node specimens found Langerhans cells coupled with eosinoph...

2015
Frédéric Grosjean Sonia Nasi Pascal Schneider Véronique Chobaz Alexandra Liu Vanessa Mordasini Kristell Moullec Paolo Vezzoni Christine Lavanchy Nathalie Busso Hans Acha-Orbea Driss Ehirchiou Luc Malaval

Langerhans cell histiocytosis (LCH) is a rare disease caused by the clonal accumulation of dendritic Langerhans cells, which is often accompanied by osteolytic lesions. It has been reported that osteoclast-like cells play a major role in the pathogenic bone destruction seen in patients with LCH and these cells are postulated to originate from the fusion of DCs. However, due to the lack of relia...

ژورنال: مجله دندانپزشکی 2006
احمدی, راحیل , رامیار, اصغر , سراج, بهمن , قدیمی, سارا ,

Langerhans cell histiocytosis (LCH) is a rare disease with formation of granulomatous infiltrations consisting of Langerhans cells, histiocytes, lymphocytes and eosinophilic granulocytes. The ethiopathogenesis of the disease has not been fully clarified yet. It can occur as focal or disseminated form - acute or chronic. Oral manifestations may be the first signs. This article reports a case of ...

Journal: :jundishapur journal of microbiology 0
maliheh khoddami pediatric pathology research center, shahid beheshti uninversity of medical sciences, tehran, ir iran mahsa vahdatinia department of community oral health, dental research center, dentistry research institute, school of dentistry, tehran university of medical sciences, tehran, ir iran seyed alireza nadji department of pathology, medical school, shahid beheshti uninversity of medical sciences, tehran, ir iran paria dehghanian virology research center, national research institute of tuberculosis and lung diseases (nritld), shahid beheshti university of medical sciences, tehran, ir iran; pediatric infectious disease research center, shahid beheshti uninversity of medical sciences, tehran, ir iran ahmad reza shamshiri department of community oral health, dental research center, dentistry research institute, school of dentistry, tehran university of medical sciences, tehran, ir iran

results there was a significant difference in prevalence of ebv presence between patients and controls. the ebv was found by rt-pcr in 19 (63.33%) out of 30 patients and only in eight (26.7%) of 30 control samples. the p = 0.004, was calculated using chi-square test (or: 4.75; 95% ci: 1.58 ‒ 14.25). conclusions our study is the first investigation performed on patients with lch and its possible...

Journal: :Haematologica 1996
V Conter A Reciputo C Arrigo N Bozzato A Sala M Aricò

Langerhans' cell histiocytosis (LCH) is an uncommon disorder of childhood, formerly referred to histiocytosis X. A significant proportion of children with disseminated disease may undergo progression to a fatal outcome despite chemotherapy with single or multiple agents. Only six cases of LCH treated with BMT have been reported in the literature, including two cases of autologous BMT. Of them, ...

Journal: :Journal of neurology, neurosurgery, and psychiatry 1995
H Goldberg-Stern R Weitz R Zaizov M Gornish N Gadoth

Langerhans cell histiocytosis (LCH), formerly known as histiocytosis-X, manifests by granulomatous lesions consisting of mixed histiocytic and eosinophilic cells. The hallmark of LCH invasion into the CNS is diabetes insipidus, reflecting local infiltration of Langerhans cells into the posterior pituitary or hypothalumus. In five patients who had early onset LCH with no evidence of direct invas...

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