PURPOSE Tears are known to have antimicrobial properties. The authors investigated the presence of the antibacterial enzyme phospholipase A2 (PLA2) in tears and lacrimal glands. METHODS The catalytic activity of PLA2 and the amount of pancreatic group 1 PLA2 and nonpancreatic group 2 PLA2 were measured in homogenates of eight human lacrimal glands from autopsied subjects and in tears from fou...

purpose : to report a patient with orbital tuberculosis (tb) without any history of systemic involvement case report : a 41-year-old afghani man who presented with progressive painless swelling in lateral side of the left upper eyelid and diplopia. he did not have history of fever or pulmonary disease. histopathology revealed a granulomatous inflammation with caseation necrosis. microbiological...

PURPOSE Previous studies have implicated androgens and one or more as yet unknown pituitary or pituitary-dependent factors in the regulation of certain lacrimal gland functions. Many observations suggest that prolactin (PRL) might well be one of these factors. This study was designed to determine the effect of hypophysectomy on biochemical markers of exorbital lacrimal gland secretory capacity ...

Purpose Adenoid cystic carcinoma (ACC) in the lacrimal gland is a rare malignancy. P16 is encoded by the CDKN2A gene, which is recognized as a tumor suppressor due to its inactivation in many types of tumors. However, p16 overexpression is also linked to adverse tumor parameters. These contradictory observations have also been confirmed in ACCs in the salivary glands. Furthermore, evidence of h...

This study aims to observe the effects of estradiol and Cimicifuga racemosa on the lacrimal gland and submandibular gland of ovariectomized rats. We randomly divided 20 adult female SD rats into four groups-a sham-operated group (SHAM), ovariectomized (OVX) group, ovariectomized group treated with estradiol (OVX+ E), and ovariectomized group treated with the isopropanolic extract of Cimicifuga ...

A case is described of a 25-year-old male who developed angiolymphoid hyperplasia with eosinophilia involving the tissue over the left parotid gland and subsequently involving the right lacrimal gland with proptosis. Treatment was by excision.

PURPOSE To assess the morphology and physiologic response of intact rabbit lacrimal acini maintained in culture for as long as 14 days and to compare the characteristics of the cultured acini with untreated fresh lacrimal gland, incubated lacrimal tissue slices, and freshly isolated acini. METHODS Acini were obtained by enzymatic digestion of lacrimal glands of adults male New Zealand white r...

Solitary fibrous tumor (SFT) is a spindle cell neoplasm of mesenchymal origin that typically arises from the pleura. Several extrapleural sites have also been described, including the orbit, lacrimal gland fossa, and lacrimal sac. We present the clinical, imaging, and histopathologic findings of an SFT arising from the sclera that manifested as an intraocular mass with extrascleral extension.