Background: Extracellular vesicles are particles ranged from 30 nm to 5µm and subcategorized into three groups; exosomes, microvesicles and apoptotic bodies, each of which have different biological impact. Lack of a standard method for the detection and isolation of MVs has led to a challenging issue that is a worth considering. In this study, we isolated MVs from the conditioned medium o...

REVIEWER COMMENTS. There is growing interest in the use of probiotic supplementation to prevent or modulate atopic disease. The authors had previously shown that prenatal and postnatal probiotic supplementation with L reuteri reduced both allergic sensitization and prevalence of IgEassociated atopic dermatitis at 2 years of age. This study further demonstrated a general reduction in production ...

BACKGROUND Islet transplantation is a viable treatment alternative for a select group of patients with type 1 diabetes. However, variables unique to the donor pancreas, such as age, fibrosis and edema, can influence the number and purity of the isolated islets. Thus isolation of a sufficient number of islets for transplantation from the pancreas remains challenging because of the lack of method...

Contents 1. Introduction: the welfare implications of pedigree dog breed standards 2. Current and future breeding trends 3. The prevalence of breed-related disease and abnormality 4. Breeds affected by hereditary hip and elbow dysplasia 4.1 The British Veterinary Association/Kennel Club hip and elbow dysplasia schemes 4.2 International studies of the prevalence of hip and elbow dysplasia 5. Bre...

This study attempts to provide a deeper insight into the current genetic status of 12 Bulgarian autochthonous sheep breeds using microsatellite (SSR) markers. A total 600 individuals from 50 flocks were analyzed panel 13 SSR In total, 228 alleles found in studied loci. The mean number alleles, effective and polymorphic information content (PIC) values per locus 17.54, 5.250, 0.799, respectively...