In order to investigate the morphological effects of ketoconazole on hypertrophied placentas, we examined the sequential histopathological changes in the placenta from rats exposed to ketoconazole. Ketoconazole was administered orally at 0 and 25 mg/kg/day during gestation days (GDs) 12 to 14, and the placentas were sampled on GDs 15, 17 and 21. All dams showed neither effect on body weight nor...

UNLABELLED Dizziness is common among the elderly. AIM To characterize social, demographic, clinical, functional and otoneurological data in elderly patients with chronic vestibular disorder. METHOD A sequential study of 120 patients with chronic vestibular disorder. Simple descriptive analyses were undertaken. RESULTS Most of the patients were female (68.3%) with a mean age of 73.40+/-5.7...

Labyrinth seal systems are used in aeroengines to the clearance, understanding of wear mechanism labyrinth system is necessary achieve better sealing performance. In this work a series tests conducted on high-speed test rig capable fin tip speeds 100 m/s. With force and temperature measurements recorded each case, influence specimen geometry investigated. Surface examination debris analysis als...

Front cover: Bony labyrinth shown in a hatching Crocodylus porosus, based on computed tomography scan. See J.A. Schwab et al., 'Ontogenetic variation the crocodylian vestibular system.

Extraembryonic ectoderm differentiation and chorioallantoic attachment are fibroblast growth factor (FGF)- and transforming growth factor beta-regulated processes that are the first steps in the development of the placenta labyrinth and the establishment of the fetal-maternal circulation in the developing embryo. Only a small number of genes have been demonstrated to be important in trophoblast...

PURPOSE To determine whether the bony and soft-tissue obliterations of the intralabyrinthine fluid spaces reported in pathologic studies of patients with Cogan syndrome can be detected with MR or CT. METHODS The inner ears of six patients with Cogan syndrome were studied. High-resolution CT was performed in five patients; all six patients were studied with MR, including T1-weighted spin-echo ...

Numerous investigators have remarked upon the secretory appearance of the labyrinth and coelomosac of the crayfish antennal gland (e.g. Marchal, 1892; Peters, 1935; Maluf, 1939). It is readily observed in stained sections that vesicles are formed at the lumenad borders of the labyrinth cells. Furthermore, the cells of the coelomosac appear to be filled with vacuoles containing granular material...

A STUDY of the circulation in the labyrinth, to be complete, must include an investigation of the fluid circulation. The fluid system in the labyrinth is much more complex than that of the cerebrospinal axis. In the latter, the cerebrospinal fluid, produced by the choroid plexuses, circulates by known anatomical pathways and its main function is the protection of the brain. In the labyrinth, ho...