نتایج جستجو برای: l23

تعداد نتایج: 296  

Journal: :Environmental Health Perspectives 1995
J F Medlin

We have compared the effects of a and recombinant y interferons (IFNs) on the growth of human lung cancer cell lines in vitro. There was a diversity of response amongst the lines studied, the most sensitive being COR-L23 (a large cell anaplastic carcinoma line) and POC (a small cell line). In these two lines. IFN-y was found to be more potent than IFN-a. During cell growth of line POC in the pr...

Journal: :European Journal of Management and Marketing Studies 2021

Entrepreneurship has always been women's interest, and women have risen in the business arena. On other hand, statistic shows that Malaysian participation entrepreneurship is still minute but vital to Malaysia's economic development, as indicated by previous researchers. Additionally, impact of Covid-19 pandemic caused adverse effects on women-owned businesses Malaysia. This research aims offer...

Journal: :Oncology reports 2015
Henghu Fang Jingbo Kang Rui Du Xiangfei Zhao Xinhong Zhang Dongqing Ren Yafei Zhang Zejun Lu Shanshan Wu Wei Zheng Juyi Wen

A large body of evidence has established murine double minute 2 (MDM2) as a crucial negative regulator of p53 and the major suppressor of p53 function in tumors with wild-type (wt)-p53. Therefore, by inhibiting MDM2 one may reactivate p53 in tumor cells, leading to their demise. Previous studies revealed that ribosomal protein L23 (RPL23) inhibited MDM2-mediated p53 ubiquitination through direc...

Journal: :Oncology reports 2013
Ya-Fei Zhang Bi-Cheng Zhang An-Ran Zhang Ting-Ting Wu Jian Liu Li-Fang Yu Wei-Xing Wang Jian-Fei Gao Dian-Chun Fang Zhi-Guo Rao

Induction of murine double minute 2 (MDM2) expression is thought to be a determinant of resistance to p53 gene therapy for cancer. Previous studies have revealed that ribosomal protein L23 (RPL23) inhibits MDM2-mediated p53 degradation through direct binding to MDM2. In addition, ectopically expressed RPL23 was reported to interact with MDM2 in both the nucleus and cytoplasm, by which RPL23 ind...

Journal: :Industrial Crops and Products 2021

Climate modelling predicts a warmer climate for cotton growing regions in the future. This will impose stresses on plants that may impact fiber cuticle wax levels, and turn make textile products more challenging to scour dye. While previous research has measured effect of abiotic stress leaves bracts, no is known have been undertaken specifically measuring content. Five Upland (Gossypium hirsut...

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