نتایج جستجو برای: krebs cycle
تعداد نتایج: 276207 فیلتر نتایج به سال:
Aconitase 2 (ACO2) encodes the mitochondrial aconitase (ACO2), an enzyme catalyzing interconversion of citrate into isocitrate in the Krebs cycle. ACO2mutations have been initially associated with infantile cerebellar-retinal degeneration combining optic atrophy, retinal degeneration, severe encephalopathy, epilepsy, and cerebellar ataxia; subsequently, ACO2 mutations have also been associated ...
Receptor-evoked Ca(2+) influx is mediated by store-operated Ca(2+) channels, such as the CRAC channel, which mediates the I(crac) current. Recent work reveals that pyruvate, the precursor substrate for the Krebs cycle, regulates I(crac) to prolong Ca(2+) influx into the cell, thereby coupling oxidation of glucose and its own metabolism in the mitochondria to Ca(2+) influx by the CRAC channel.
Magnesium is an important constituent of cardiac and skeletal muscle, of nerve tissue and bone. It is involved in protein, fat, nucleic acid and coenzyme synthesis; in glucose utilization and in neuromuscular activity. It is also an essential acti vator for several enzymes, some that transfer phosphate, some that are in volved with the decarboxylation of pyruvic acid and others concerned with r...
Evidence against the occurrence of the Krebs oxidation cycle in bacterial respiration has been steadily accumulating. Escherichia coli and many other bacteria do not readily metabolize the three tricarboxylic acids. Aerobacter aerogenes will not readily attack citrate when measured manometrically unless the organism is grown in the presence of this acid as the sole source of carbon. Recently Le...
Metabolic remodeling is a major determinant for many cell fate decisions, and a switch from respiration to aerobic glycolysis is generally considered as a hallmark of cancer cell transformation. Pyruvate is a key metabolite at the major junction of carbohydrate metabolism between cytosolic glycolysis and the mitochondrial Krebs cycle. In this issue of The EMBO Journal, Bender et al show that ye...
در این پایان نامه خصوصیات کلی شبیه سازی cycle-based معرفی شده و نحوه انجام شبیه سازی cycle-based در سطح گیت و سطح انتقال ثبات مورد بررسی موشکافانه قرار گرفته است . در این پایان نامه همچنین محدودیتهای شبیه سازی cycle-based معرفی شده و راه حلهایی برای این مشکلات ارائه شده است . به موازات این پایان نامه و برای اثبات صحت نظریه های مطرح شده و راه حلهای ارائه شده در آن، یک شبیه ساز cycle-based برای ز...
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