PURPOSE Comparative drug release kinetics from nanoparticles was carried out using conventional and our novel models with the aim of finding a general model applicable to multi mechanistic release. Theoretical justification for the two best general models was also provided for the first time. METHODS Ten conventional models and three models developed in our laboratory were applied to release ...

The biological activity of the immobilized enzyme is crucial for the performance of different nanoparticle mediated enzymatic assays, where enzymatic conversion can be used for label-free analyte detection. In this article we have addressed two significant aspects of enzyme-nanoparticle interactions. First, we have developed copper sulfide (CuS) nanoparticles with an average diameter of 25 nm a...

results analysis by xrd showed 78.1% zno (sized 24 nm), 2.5% zn (sized 44.88 nm) and 4.8% zns (sized 12 nm) produced by p. stutzeri. the nanoparticles showed anti-bacterial activity against some of the gram positive and negative bacteria. in addition, the nanoparticles showed magnetic properties. the best condition for nano zinc production was at ph 7, in the light and at 37 °c. czcc gene with ...

Core-shell nanostructures are emerging as more important materials than alloy nanostructures and have much more interesting potential applications in various fields. In this work, we demonstrated the fast and facile synthesis of core-shell nanoparticles consisting of Pt thin layer as the shell and Ni nanoparticles as the cores. The described method herein is suitable for large-scale and low-cos...

Zinc sulfide (ZnS) & zinc oxide (ZnO) nanoparticles was evaluated for their antimicrobial activity against four pathogenic strains. ZnS&ZnO nanoparticles were synthesized by simple aqueous chemical reaction in an aqueous solution. The main advantage of these nanoparticles (size of 10-30 nm) was that simply could be prepared by using cheap precursors in a cost effective and high throughput manne...

protein aggregation is a problem in biotechnology. high temperature is one of the most important reasons to enhance enzyme inactivation and aggregation in industrial systems. this work focuses on the effect of tio2 and sio2 nanoparticles on refolding and reactivation of lysozyme. in the presence of tio2 and sio2 nanoparticles, after enzyme heat treatment at 98◦c for 30 min, not only aggregates ...

Three-dimensional ordered lattices of nanoparticles linked by DNA have potential applications in novel devices and materials, but most experimental attempts to form crystals result in amorphous packing. In this thesis, a coarse-grained model is used to address three factors which impact the kinetic and thermodynamic stability of BCC and FCC crystals formed in DNA-linked nanoparticle systems: (i...