نتایج جستجو برای: kinase protein regulation
تعداد نتایج: 1666231 فیلتر نتایج به سال:
Purpose: To investigate the influence of elemene on growth and apoptotic changes in bladder cancer cells, involvement phosphatase tensin homologous protein (PTEN)-serine/threonine kinase (Akt) signal pathway process.
 Methods: Human cell line SV-HUC-1 human T24 were randomly assigned to blank control group groups. Protein expression levels apoptosis-related factors (Bcl-2, Bax, caspase-3] ...
We show that treatment of a panel of thyroid carcinoma cell lines naturally harboring the RET/PTC1 oncogene, with the RET kinase inhibitors PP1 and ZD6474, results in reversible G(1) arrest. This is accompanied by interruption of Shc and mitogen-activated protein kinase (MAPK) phosphorylation, reduced levels of G(1) cyclins, and increased levels of the cyclin-dependent kinase inhibitor p27Kip1 ...
We examined regulation of the Na(+)/H(+) exchanger isoform 1 by phosphorylation in the rat myocardium. We utilized cell extracts from adult rat hearts, adult rat extracts fractionated by fast performance liquid chromatography, and extracts from cultured neonatal cardiac myocytes. The carboxyl-terminal 178 amino acids of the Na(+)/H(+) exchanger were expressed in Escherichia coli fused with glut...
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