introduction: due to its immunosuppressive properties, local graft irradiation (lgi) has been proposed as a second line therapy for treatment of acute kidney rejection. case presentation: in this case-series we report 6 patients with biopsy proven acute kidney allograft rejection refractory to conventional antirejection therapy who underwent lgi for treatment of acute rejection at our center. t...

Acute interstitial nephritis is among the causes of abdominal pain. We aimed to demonstrate acute nephritis, which can occur after intentional drug use as a suicide attempt and be confused with abdomen. A 15-year-old girl described She was referred nephrology department because her serum creatinine value 3.4 mg/dL. Although patient asked about any use, she stated that had not taken medication. ...

OBJECTIVE To study the diagnostic yield of specimen obtained by percutaneous renal biopsy (PRB) under CT guidance and Ultrasound (US) guidance. METHODS This study was conducted at the department of Nephrology at Liaquat National Hospital and Dr. Ziauddin Hospital, Karachi. Renal biopsy specimens obtained between January 2007 and September 2009 were studied for number of glomeruli obtained. In...

Introduction: For renal diseases, renal biopsy is considered gold standard to reach a diagnosis. The present study was undertaken to understand and analyze clinical symptoms, lab findings and final histological diagnosis for clinico-pathological correlation. Material and Methods: The present prospective study comprised of 127 patients who underwent per-cutaneous renal biopsies over a period of ...

PURPOSE Historically, the biopsy of renal masses was not advocated, and to date there remains some controversy on the role of biopsy for renal masses in making treatment decisions. With the widespread use of imaging methods, the incidental diagnosis of renal masses has increased, necessitating renal biopsies to better plan the management of these tumours. Here I review previous reports to defin...

[This corrects the article DOI: 10.1016/j.krcp.2013.04.006.].

INTRODUCTION The kidney biopsy is used to diagnose and guide initial therapy in patients with lupus nephritis (LN). Kidney histology does not correlate well with clinical measurements of kidney injury or predict how patients will respond to standard-of-care immunosuppression. We postulated that the gene expression profile of kidney tissue at the time of biopsy may differentiate patients who wil...

A young renal transplant recipient received living kidney from his father; the Centers for Disease Control and Prevention (CDC) cross match was all negative. He had oliguria 5 hours after with fever neutrophil leukocytosis. Doppler ultrasonogram revealed increased cortical echo Resistive Index suggesting acute rejection or tubular necrosis. Renal biopsy T cell mediated (acute TCMR) Grade IIA. T...