The bacterial parD toxin-antitoxin system of plasmid R1 encodes two proteins, the Kid toxin and its cognate antitoxin, Kis. Kid cleaves RNA and inhibits protein synthesis and cell growth in Escherichia coli. Here, we show that Kid promotes RNA degradation and inhibition of protein synthesis in rabbit reticulocyte lysates. These new activities of the Kid toxin were counteracted by the Kis antito...

BACKGROUND The pediatric quality of life (QoL) questionnaire, the child-rated Kid-KINDL, has wording effects. However, no studies have examined for its parallel questionnaire, the parent-proxy Kid-KINDL. This study aimed to examine the psychometric properties and wording effects of the parent-proxy Kid-KINDL. METHODS Parents with 8- to 12-year-old children (n = 247) completed the parent-proxy...

the objective of this study was to evaluate the effects of weaning age on dry matter intake (dmi), average daily gain (adg), feed efficiency (fe), feed cost (fc) and benefit index (bi) of holstein calves reared under organic farming system. thirty two holstein calves were divided into two treatments: early weaning (ew) vs. late weaning (lw). calves in the both groups were provided with whole mi...

BACKGROUND The aim of this study is to evaluate a percutaneous left ventricular assist device (Tandem Heart pVAD; Cardiac Assist, Pittsburgh, Pennsylvania) in the postcardiotomy setting. METHODS Between August 2001 and August 2004, 11 high-risk male patients who had undergone heart failure surgery or surgical revascularization were supported by the TandemHeart postcardiotomy. The major indica...

This study examined the reproductive performance of dihydroxy pyridone (DHP)-inoculated South African indigenous (SAIG) female goats maintained on two dietary treatments: (i) Leucaena leucocephala/grass mixture and (ii) natural pasture prior to conception, and during gestation. Leucaena leucocephala/grass mixture was nutritionally superior (crude protein and mineral elements) than the natural p...

The efficiency of Simmentaler cross (SX), Bonsmara cross (BX), Afrikaner (AF) and Nguni (NG) cowherds to produce weaner calves under natural sweetveld conditions was investigated. The respective cowherds were selected to differ with regard to frame size (SX > BX > AF > NG). The AF cows, young (13 to 15 months old) heifers and herd had significantly lower pregnancy rates than the SX, BX and NG c...

Toward the end of mitosis, neighboring chromosomes gather closely to form a compact cluster. This is important for reassembling the nuclear envelope around the entire chromosome mass but not individual chromosomes. By analyzing mice and cultured cells lacking the expression of chromokinesin Kid/kinesin-10, we show that Kid localizes to the boundaries of anaphase and telophase chromosomes and co...

Gary Becker's \Rotten Kid Theorem" asserts that if all family members receive gifts of money income from a benevolent household member, then even if the household head does not precommit to an incentive plan for family members, it will be in the interest of sel sh family members to maximize total family income. We show by examples that the Rotten Kid theorem is not true without assuming transfe...

OBJECTIVES To investigate the therapeutic impact of combining extracorporeal membrane oxygenation (ECMO) and early coronary revascularization on acute myocardial infarction (AMI)-induced cardiopulmonary collapse. MATERIALS AND METHODS This retrospective study included 35 consecutive patients rescued by ECMO for AMI-induced cardiopulmonary collapse in a single institution between June 2003 and...