STATEMENT OF THE PROBLEM Squamous cell carcinoma (SCC) is the most frequent oral cancer whose 5-year survival rate is 80% for early-detected lesions and nearly 30-50% for advanced lesions. Early detection of oral cancers and precancerous lesions can improve the patient's survival and decrease the morbidity. PURPOSE This study aimed to evaluate and compare the Ki-67 and MCM3 expression in cyto...

The current World Health Organization (WHO) classification of human gliomas is mainly based on morphology. However, it has limitations in prognostic prediction. We examined whether combining isocitrate dehydrogenase (IDH) 1/2 mutation status with the Ki-67 labeling index would improve the definition of prognostically distinct entities. We investigated the correlation of Ki-67 expression with ID...

A dose-response study was performed in adult rats to select an optimal stable potassium iodide (KI) dose which could be implemented in repeated prophylaxis, in case of prolonged exposure to radioactive iodine. Increasing doses of KI were given orally to rats 1 hour before internal exposure simulated by I-125 injection. I-125 incorporation in the thyroid was measured by γ-spectrometry, and KI pr...

BACKGROUND Studies have partly demonstrated the clinical validity of Ki-67 as a predictive marker in the neoadjuvant setting, but the question of the best cut-off points as well as the importance of this marker as a prognostic factor in partial responder/non-responder groups remains uncertain. METHODS One hundred twenty patients diagnosed with invasive breast cancer and treated with neoadjuva...

AIMS To study the expression of Ki-67 and cytokeratin 20 (CK20) in a group of hyperplastic polyps (including a group with "atypical" features) with the aim of determining whether upper crypt Ki-67 staining and lower crypt CK20 staining correlated with these atypical features, as assessed by light microscopy. METHODS Fifty seven formalin fixed, paraffin wax embedded hyperplastic colorectal pol...

We immunohistochemically examined specimens of 215 surgically resected non-small cell lung cancers (NSCLCs) for p27KIP1 protein (p27) expression and the growth fraction determined by the Ki-67 labeling index (LI). The NSCLCs analyzed showed considerable heterogeneity in both p27 and Ki-67 LIs; 25 of 207 (13%) lacked p27 expression (p27 LI < 5%), and 116 of 215 (54%) showed a high Ki-67 LI (>30%...

die KI-Zeitschrift wird sich bald verändern. Die Leitung des Fachbereiches KI in der GI und die Herausgeber der KI sind auf der Suche nach einem neuen Verlag. Wir haben zehn Jahre sehr gut und zuverlässig mit Tarik Böttcher zusammengearbeitet, den viele von Ihnen auch kennen werden, wenn Sie in der KI publiziert haben. Gründe für den Verlagswechsel gibt es mehrere: finanzielle und konzeptionell...

Osnovno aplikacijo video nadzora, ki je nekakšen ekvivalent standardnim nadzornim sistemom, ki niso računalnǐsko podprti, si lahko predstavljamo enostavno kot povezavo med računalnikom in kamero. Računalnik zajema podatke in jih prikazuje na ekranu. Seveda moramo v tem primeru zagotoviti prisotnost varnostnika, ki opazuje dogajanje na ekranu, saj ima računalnik tukaj le funkciji zajemanja in pr...