Airway hyper-responsiveness associated with asthma is mediated by airway smooth muscle cells (SMCs) and has a complicated etiology involving increases in cell contraction and proliferation and the secretion of inflammatory mediators. Although these pathological changes are diverse, a common feature associated with their regulation is a change in intracellular Ca(2+) concentration ([Ca(2+)](i))....

A kinematical 3D model for hyper-redundant robots is created. A development environment for control applications for tentacle robots is created. This environment includes a personal library of mathematical functions typical for tentacle robots, a complex graphical engine to represent realist animations to illustrate the plane motion of the hyper-redundant robots, and a library of programming fu...

In this paper, we selected three different CPU architectures for performance analysis: single-core, dualcore and hyper-threading CPU’s. Four kinds of operations are executed on these architectures. After analyzing all the data, we found that the single-core and dual-core act as usually expected: the execution times of combined operations are very close to the sum of that of compounding operatio...

Allergic airways disease is a consequence of a Th2 response to an allergen leading to a series of manifestations such as production of allergen-specific IgE, inflammatory infiltrates in the airways, and airway hyper-reactivity (AHR). Several strategies have been reported for tolerance induction to allergens leading to protection from allergic airways disease. We now show that CD4 blockade at th...

Asthma is a complex disease of airway inflammation, which results in airway remodeling and hyper-responsiveness.1 Because asthma-related symptoms are not specific to asthma, diagnosis requires objective data from pulmonary function tests (PFT). Bronchodilator responsiveness and airway responsiveness to provocational stimuli (eg, methacholine, dry-gas hyperpnea) help establish the diagnosis of a...

Asthma is a common respiratory disorder that characterized by airway hyper-reactivity and chronic inflammation. gastroesophageal reflux disease can occur together, both affect each other. We represent 41 years old male patient with chief complaint of asthma preceded burning sensation on his throat also heartburn over the last three months. Patient had visited family doctor but symptom still occ...

crouzon syndrome is a rare autosomal dominant premature cranyosynostosis, caused by fibroblast growth factor receptor 2 gene mutation on chromosome 10. the predominant skull and facial malformations with potential compromise airway make the crouzon syndrome a demanding issue for anesthesiologists and surgeons, required dynamic team work. in this report we describe a child, a known case of crouz...

Deep inspirations (DIs) and airway smooth muscle fluidization are two widely studied phenomena in asthma research, particularly for their ability (or inability) to counteract severe airway constriction. For example, DIs have been shown effectively to reverse airway constriction in normal subjects, but this is impaired in asthmatics. Fluidization is a connected phenomenon, wherein the ability of...