keratinolytic activity

nowadays, the development of anti cancer drugs is an important subject in pharmacology. bisphosphonates (b.p) are a great choice for design and production of the types of drugs which not only could perform as anti cancer agents but also could inhibit the function of acetyl cholinesterase (ache). ache hydrolyzes the acetylcholine (which is a neurotransmitter in nervous system) using the oh in i...

Probing the Crucial Role of Leu31 and Thr33 of the Bacillus pumilus CBS Alkaline Protease in Substrate Recognition and Enzymatic Depilation of Animal Hide

2014

Nadia Zaraî Jaouadi Bassem Jaouadi Hajer Ben Hlima Hatem Rekik Mouna Belhoul Maher Hmidi Houda Slimene Ben Aicha Chiraz Gorgi Hila Abdessatar Toumi Nushin Aghajari Samir Bejar Pratul K. Agarwal

The sapB gene, encoding Bacillus pumilus CBS protease, and seven mutated genes (sapB-L31I, sapB-T33S, sapB-N99Y, sapB-L31I/T33S, sapB-L31I/N99Y, sapB-T33S/N99Y, and sapB-L31I/T33S/N99Y) were overexpressed in protease-deficient Bacillus subtilis DB430 and purified to homogeneity. SAPB-N99Y and rSAPB displayed the highest levels of keratinolytic activity, hydrolysis efficiency, and enzymatic depi...

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biological screening of euphorbia aellenii

Journal: :iranian journal of pharmaceutical research 0

abdul majid ayatollahi phytochemistry research center and school of pharmacy, shaheed beheshti university of medical sciences, tehran, iran. mustafa ghanadian isfahan pharmaceutical sciences research center, isfahan university of medical sciences, isfahan, iran. suleiman afsharypuor isfahan pharmaceutical sciences research center, isfahan university of medical sciences, isfahan, iran. sadia siddiq dr. panjwani center for molcular medicine and drug research, international center for chemical and biological sciences, university of karachi,karachi, pakistan. muhammad pour-hosseini medical genetic department, faculty of medicine, shaheed beheshti university of medical sciences, tehran, iran.

fractions obtained from partitioning of aerial methanolic extract of euphorbia aellenii with chloroform (e2), ethyl acetate (e3), n-butanol (e4) and water (e5) were investigated in vitro for their phytotoxicity, insecticidal, anti-leishmanial, cytotoxicity, antibacterial and antifungal activities. sample e2 appeared to have significant phytotoxic activity. in the insecticidal screening study on...

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