Abstract Introduction Hydrogen sulfide (H2S) is an endogenously produced gaseous cellular signaling molecule with vasodilatory, anti-inflammatory, and antioxidant-like properties. H2S thought to protect against oxidative stress through activation of transcription factor(s) that transcribe genes involved detoxification antioxidant defense. We have previously used a Western diet (WD) high in fat ...

The dynamic behavior of liquid droplets on a reconstructed real gas diffusion layer (GDL) surface with the inertial effect produced by three dimensional (3D) flow channel is investigated using an improved pseudopotential multiphase model within unified lattice Boltzmann (ULBM) framework, which can realize thermodynamic consistency and tunable tension. microstructure GDL (Toray-090) including ca...

The influence of the different properties gas diffusion layer (GDL) on operation a liquid-cooled, proton-exchange polymer electrolyte fuel cell (PEMFC) has been studied in this work. Three-dimensional numerical simulations (CFD) have conducted to compare several commercial GDLs with properties, analyzing their performance. Specifically, four (AvCarb P-75, SIGRACET 34BC, 34BA and Toray TGP-H-090...

Nephropathic subjects show an increased tendency to develop cardiovascular diseases, mainly as the consequence of several risk factors including increased oxidative stress, inflammation, physical inactivity, anemia, vascular calcification, and endothelial dysfunction. The alterations in lipid metabolism represent a relatively lesser important cause of genesis and progression of atherosclerosis....

The somatostatin receptors on rat pancreatic acinar membranes were demonstrated by use of a radioiodinated (125I-) analogue of somatostatin (SMS 204-090 or [Tyr3]SMS). The tracer was found to bind to the receptor with a Kd of 58 pM. The number of sites detected by this tracer (4.7 pmol/mg of protein) was 5-10 times higher than the number of sites previously found with other tracers. Since the l...

The present manuscript reviews the study of Delany et al. on the impact of herpes simplex virus type 2 (HSV-2) suppressive aciclovir on genital and plasma HIV-RNA in 269 HSV-2/ HIV-coinfected women in South Africa [1]. HIV infection continues to be among the leading causes of global morbidity and mortality, especially in Africa. An estimated 40 million people are HIV positive with an annual mor...