The ErbB1 and ErbB2 receptors are oncogenes with therapeutic significance in human cancer, whereas the transforming potential of the related ErbB4 receptor has remained controversial. Here, we have addressed whether four alternatively spliced ErbB4 isoforms differ in regulating cellular responses relevant for tumor growth. We show that the two tumor necrosis factor-alpha converting enzyme (TACE...

s and Proceedings Fowlkes JB, Gardner EA, Carson PL, Ivey JA, Rubin JM: "Acoustic Interruption of Ultrasound Contrast Agents for Blood Flow Evaluation", Procs., 39th Annual Conv. of the American Institute of Ultrasound in Medicine, San Francisco, CA, March 26-29, 1995. Rubin JM, Adler RS, Fowlkes JB, Spratt S, Pallister JE, Chen J-F, Carson PL (1995) Fractional Moving Blood Volume Estimation Us...

The availability of numerous spectral, spatial, and contextual features renders the selection of optimal features a time consuming and subjective process in object-based image analysis (OBIA). While several feature selection methods have been used in conjunction with OBIA, a robust comparison of the utility and efficiency of approaches could facilitate broader application. In this study, we tes...

1. Knopp S, Bjorge T, Nesland JM, Trope C, Scheistroen M, Holm R. p16INK4a and p21Waf1 ⁄ Cip1 expression correlates with clinical outcome in vulvar carcinomas. Gynecol. Oncol. 2004; 95; 37–45. 2. Knopp S, Bjorge T, Nesland JM, Trope C, Holm R. Cyclins D1, D3, E, and A in vulvar carcinoma patients. Gynecol. Oncol. 2005; 97; 733–739. 3. McKay JA, Douglas JJ, Ross VG et al. Expression of cell cycl...

BACKGROUND Altered expression of apicobasal polarity factors is associated with cancer in vertebrates and tissue overgrowth in invertebrates, yet the mechanisms by which these factors affect growth-regulatory pathways are not well defined. We have tested the basis of an overgrowth phenotype driven by the Drosophila protein Crumbs (Crb), which nucleates an apical membrane complex that functional...

Very few empirically validated interventions for improving metacognitive skills (i.e., self-awareness and self-regulation) and functional outcomes have been reported. This single-case experimental study presents JM, a 36-year-old man with a very severe traumatic brain injury (TBI) who demonstrated long-term awareness deficits. Treatment at four years post-injury involved a metacognitive context...

1. Baïri A, Zarco-Pernia E, García de María JM. A review on natural convection in enclosures for engineering applications. The particular case of the parallelogrammic diode cavity Applied Thermal Engineering, 2014;63:304-322. http://dx.doi.org/10.1016/j.ap.... CrossRef Google Scholar