Breaching endothelial cells (ECs) is a decisive step in the migration of leukocytes from the vascular lumen to the extravascular tissue, but fundamental aspects of this response remain largely unknown. We have previously shown that neutrophils can exhibit abluminal-to-luminal migration through EC junctions within mouse cremasteric venules and that this response is elicited following reduced exp...

In this study, the interactions of enterohemorrhagic Escherichia coli (EHEC) O157 strains with human ileocecal (HCT-8) epithelial cells and HEp-2 cells were examined. EHEC adhered to, but did not invade, HCT-8 cells by the localized adherence mechanism and a heretofore unrecognized pattern which we called log jam. The log jam formation was (i) not observed on HEp-2 cells, (ii) independent of th...

Exploring the role of junctional adhesion molecules (JAMs) has proven to be varied and controversial. The purpose of this review is to discuss the new and exciting roles of these IgSF molecules and how they have evolved to contribute to diverse functions from development to inflammation. In particular, recent research has focused on JAM subfamily members JAM-A, -B, and -C with newly described r...

Evaluation of biomarkers of arterial hypertension (AH) could be considered to be useful as early, more reliable and accurate diagnostic indicators for AH than simply measuring of blood pressure (BP) in routine clinical practice, especially at early stages of hypertension. For instance, an increased level of a soluble protein junctional adhesion molecule-A (JAM-A) was previously found to be asso...

Evaluation of biomarkers of arterial hypertension (AH) could be considered to be useful as early, more reliable and accurate diagnostic indicators for AH than simply measuring of blood pressure (BP) in routine clinical practice, especially at early stages of hypertension. For instance, an increased level of a soluble protein junctional adhesion molecule-A (JAM-A) was previously found to be asso...

the main purpose of this survey was to identify and analyze the barriers in women’s economic participation in the rural regions of the zanjan province. the study was an analytical- explanatory research regarding its method. the statistical population of the study were consisted of all the rural women in the abhar-rod rural district (n= 1300). according to the krejcie and morgan table, a sample ...

We study the phase diagram of the continuum traffic flow model of a highway with an on-ramp. Using an open boundary condition, traffic states and metastabilities are investigated numerically for several representative values of the upstream boundary flux f(up) and for the whole range of the on-ramp flux f(rmp). An inhomogeneous but time-independent traffic state (standing localized cluster stat...

kimia-ye sa'adat is the most important work of abu hamed mohammad ghazzali in persian which has been edited and published twice in iran: the first time in 1940/1319 š by ahmad aram, and the second time in 1982/1361 š by hossein khadiv jam who had already published the first half of the book in 1976/1355 š. this article seeks to study these two editions, especially the one by khadiv jam, and com...

Kaptein RG and Van Gisbergen JAM. Effect of gravity cues on spatial updatingduring sinusoidal rotation. Program No. 168.6. Abstract viewer/Itinerary Planner.Washington, DC: Society for Neuroscience, 2005 Kaptein RG and Van Gisbergen JAM. Bistable perception of verticality duringroll tilt. Program No. 868.3. Abstract Viewer/Itinerary Planner. Washington, DC:Society for Neuroscien...