This study investigated antioxidant and anti-inflammatory in order to confirm the possibility of functional materials that can improve skin diseases using <i>Hemistepta lyrata</i> Bunge extracts solvent fractions. As a result measuring total polyphenol content, content was high EtOAc fraction, then BuOH fraction is next. DPPH free radical scavenging activities, it confirmed fraction...

OBJECTIVES Nitric oxide and prostaglandins are both implicated in the pathogenesis of inflammatory conditions such as rheumatoid arthritis (RA). The hypothesis that simultaneous inhibition of nitric oxide synthase (NOS) and cyclooxygenase (COX) was more effective than inhibition of either enzyme alone was tested. METHODS J774 macrophages were pre-incubated with L-NAME and/or indomethacin, pri...

Recent data suggest that plasma leptin may represent a cardiovascular risk factor in diabetic patients. To gain further insight into the role of leptin in atherogenesis associated with diabetes, we investigated in the present study the role of this hormone in the regulation of macrophage lipoprotein lipase (LPL), a proatherogenic cytokine overexpressed in patients with type 2 diabetes. Treatmen...