In Vitro Maturation (IVM) is a method that immature oocytes in antral follicles are extracted and matured in laboratry conditions. This review has attempted to provide the current knowledge and recent findings in in vitro maturation of oocytes and highlights the most important factors involved in this process. The review is based on literature reports and the author’s experience. In IVM cycles,...

In vitro maturation (IVM) is emerging as a popular technology at the forefront of fertility treatment and preservation. However, standard in vitro culture conditions usually increase reactive oxygen species (ROS), which have been implicated as one of the major causes for reduced embryonic developmental competence. It is well-known that higher than physiological levels of ROS triggers granulosa ...

Background: 15% of oocytes collected in ART cycles are immature. These oocytes may be matured following IVM program. It is possible to cryopreserve the immature oocytes for further use in ART after application of IVM. The aim was to determine the maturation rate, morphology and viability of human immature oocytes after fresh IVM and vitrified-IVM program. Materials and Methods: 63 women who und...

Background Polycystic ovarian syndrome (PCOs) is one of the most common causes of infertility in women of reproductive age. Currently, one of the best therapeutic options for PCOs patients is ICSI. Moreover, IVM can be a useful technique for women with PCOs who are at the risk of ovarian hyperstimulation syndrome (OHSS). On the other hand, the oocyte quality can be a determining factor for outc...

Volume 4 • Issue 2 • 1000e124 JFIV Reprod Med Genet ISSN: 2375-4508 JFIV, an open access journal In vitro oocyte maturation (IVM) has carved a niche for itself in assisted reproductive technology (ART). In 1991, Cha et al. [1] reported the first collection of immature oocytes, which were matured in vitro and resulted in a live birth. Since then, IVM protocols have developed ranging from IVM wit...

Nitric oxide (NO) is a molecule involved in many reproductive processes. Its importance during oocyte in vitro maturation (IVM) has been demonstrated in various species although sometimes with contradictory results. The objective of this study was to determine the effect of NO during IVM of cumulus oocyte complexes and its subsequent impact on gamete interaction in porcine species. For this pur...

in vitro maturation (ivm) is emerging as a popular technology at the forefront of fertility treatment and preservation. however, standard in vitro culture conditions usually increase reactive oxygen species (ros), which have been implicated as one of the major causes for reduced embryonic developmental competence. it is well-known that higher than physiological levels of ros triggers granulosa ...

Background: Melatonin (N-acetyl-5-methoxytryptamine) is a multifunctional molecule that mediates several circadian and seasonal processes in animal reproduction. Melatonin and its metabolites are antioxidants and free radical scavengers. Furthermore, melatonin has been shown to act as an indirect antioxidant, and it is able to increase the activity of glutathione synthesis, and many others dire...

This study was conducted to establish an in vitro maturation (IVM) system by selection of efficient porcine serum during porcine in vitro production. To investigate the efficient porcine serum (PS), different types of PS [newborn pig serum, prepubertal gilt serum (PGS), estrus sow serum, and pregnancy sow serum] were used to supplement IVM media with or without gonadotrophin (GTH) and developme...

BACKGROUND This study was to examine the developmental capacity of oocytes collected from an in vitro maturation (IVM) programme according to their maturation time. METHODS The study included 47 IVM cycles that underwent blastocyst transfer. The patients (n = 38) were primed with 10 000 IU HCG 36 h before their oocyte retrieval. The oocytes were classified into three groups: group 1 (n = 139)...