Objective(s): This study was designed to investigate various gastrointestinal effects of Manilkara zapota (Sapodilla), exploring its anti-diarrheal, anti-secretary, anti-spasmodic, anti-ulcer and anti-motility potential.Materials and Methods: Antidiarrheal and anti-secretary activities were investigated using castor oil induced diarrhea ...

Naturally fermented soybean foods have anti-thrombotic properties due to the presence of microbial fibrinolytic enzymes. However, enzyme-producing bacteria from naturally Eastern Himalayas viz. kinema, grep-chhurpi, peha, peron namsing, peruñyaan and bemerthu not been screened yet. Therefore, this study aims screen these also assess their therapeutic such as antioxidant, anti-inflammatory, flav...

SOME malignancies of the extremities can be treated by hyperthermic isolated limb chemotherapy. This procedure involves arterial and venous cannulation of the affected limb and isolated perfusion using a bypass pump. When a steady state is reached, the blood is warmed and oxygenated, and a chemotherapeutic agent (e.g., melphalan) is added and circulated in the limb for up to 1 h. Because the li...

In the present study, anti-anaphylactic, anti-inflammatory and membrane stabilizing properties of a lupine alkaloid plumerianine (compound 1), isolated from the root bark of Plumeria acutifolia Poir were investigated in animal models. The anti-anaphylactic activity of compound 1 (10, 25 and 50 mg/Kg) was studied by using models such as passive cutaneous anaphylaxis, passive paw anaphylaxis and ...

Mol. Nutr. Food Res. 2023, 67, 202200385 DOI: 10.1002/mnfr.202200385 Obesity is one of the most common and chronic disease, worsening health conditions. Bifidobacterium lactis IDCC 4301 a probiotic strain previously isolated from infant feces, having anti-inflammatory properties lowering GI-symptoms. Here, anti-obesity effects have been proved by disclosing mode actions with suggestions possibl...

In an investigation into their potential ecological role(s), a group of mainly diterpene isonitriles, nine in total, isolated from the tropical marine sponge Cymbastela hooperi, and the sesquiterpene axisonitrile-3, isolated from the tropical marine sponge Acanthella kletra, were evaluated in a series of bioassays including anti-fouling, anti-algal, anti-photosynthetic, anti-bacterial (Gram +ve...

Background and objectives: Phyllanthus emblica L. (Phyllanthaceae), commonly known as Indian gooseberry, is an endemic plant to the tropical and subtropical areas in china, India and Thailand. The plant is extensively used in Chinese, Ayurveda, and traditional Persian medicine (TPM). In addition, there are numerous reports on pharmacological and clinical activities of ...