PURPOSE Nonarteritic anterior ischemic optic neuropathy (NAION) is an optic nerve (ON) infarct of retinal ganglion cell (RGC) axons, and the most common cause of ON-related sudden vision loss. Estrogen has been previously proposed as a neuroprotective treatment for central nervous system ischemia. We evaluated estrogen's potential in post-ON infarct treatment to reduce neuronal loss following a...

Anterior ischemic optic neuropathy is an acute ischemic disease of vascular origin whose treatment demands urgent application of an appropriate therapy. The research included 56 patients with an acute form of anterior ischemic optic neuropathy with 50 of them classified as idiopathic types while 6 had the arteritic form of the disease. In this paper, we analyze the therapeutic significance and ...

We present the case of a 45-year-old male patient with sudden painless visual loss in left eye (OS), diagnosed as nonarteritic anterior ischemic optic neuropathy (NAION). Three months later, new superior scotoma, accompanied by an inferior disc edema, characterized recurrent episode NAION OS. Ambulatory blood pressure monitoring disclosed arterial hypertension, no drop during sleep. Optical Coh...

Non-arteritic anterior ischemic optic neuropathy is caused by a transient optic nerve ischemia and results in permanent vision loss. Currently, there is no effective treatment for this ischemic optic nerve injury. This study characterized the duration and extent of ischemia induced after a coagulopathy injury to the optic nerve of adult rats. Acute ischemia was induced in adult rats by intraven...

purpose : to present a patient with radiation chiasma neuropathy, secondary to radiotherapy of paranasal sinus lymphoma who was referred for evaluation of gradual decrease of vision in both eyes case report : the patient was a 38-year-old male, with history of right maxillary sinus lymphoma, who underwent surgery, chemotherapy and radiation therapy. one year after radiotherapy, he noticed gradu...

PURPOSE To report the development of a bilateral ocular ischemic syndrome despite corticosteroid treatment in a patient with giant cell arteritis. METHOD Case report. RESULTS Despite receiving high-dose intravenous methylprednisolone and oral prednisone for biopsy-proven giant cell arteritis that presented as a severe anterior ischemic optic neuropathy in the right eye, a patient developed ...

We present a case of unilateral blindness with subarachnoid hemorrhage after rupture of an anterior communicating artery aneurysm. Her corrected visual acuity was 1.2 in the right eye and no light perception in the left eye. Fundus examination revealed intrarerinal and subretinal hemorrhages and optic disc atrophy in the left eye. We speculated the condition as an ischemic optic neuropathy. Alt...

BACKGROUND/OBJECTIVE The elderly have suffered from visual impairment for thousands of years. This report evaluates the first documented cases of visual disability in the elderly as described in the Bible. RESULTS Three old men suffered from a gradual loss of vision. It is more likely that either mature cataract, or age-related macular degeneration, or asymptomatic open-angle glaucoma, or isc...