Introduction: Reactive oxygen species (ROS) have been suggested to play an important role in the myocardial damage induced by ischemia – reperfusion. One element believed to be activated by ROS and to contribute to the reduction of ROS production, is the uncoupling protein-2 (UCP2). The objective of this investigation was to explore the effect of myocardial ischemia reperfusion on cardiac UC...

abstract background: infectious agents such as chlamydia pneumonia or helicobacter pylori (h. pylori) have been linked to ischemic heart disease (ihd) as the epidemiologic studies have shown. other studies believed that raised plasma fibrinogen level has been claimed as a possible link between h. pylori infection and ihd. methods: an analytic cross-sectional study was undertaken on 261 patients...

introduction hypoparathyroidism might cause various musculoskeletal findings, resembling spondyloarthropathies. case presentation we described a 52-year-old woman, diagnosed as a case of undifferentiated spondyloarthropathy for ten years, who was unresponsive to classic anti-inflammatory therapies. she developed anterior ischemic optic neuropathy and had elevated muscle enzymes during the cours...

cerebrovascular attack (cva) and transient ischemic attack (tia) are major causes of emergency department visits around the globe. a significant number of these patients may experience repeat attacks if left untreated. several risk stratifying scoring systems have been developed in recent years to point out the high risk patients. abcd 2 is based on age, blood pressure, clinical status, diabete...

objective: children with attention deficit hyperactivity disorder (adhd) do not process most information due to inattention and loss of the opportunity to save and retrieve information. therefore, these children experience memory impairment. although visual memory has been previously studied in children with adhd, iconic memory in these children has been less evaluated. we aimed to study the po...

The aim of the present study was to evaluate critically the protection afforded by hypothermia against ischemic injury to the hippocampus. Hypothermic treatment was applied selectively to the brain during a 5 min carotid artery occlusion in gerbils. Following a period of recovery, two independent measures were used to assess hippocampal function: (1) an open field test of spatial memory (assess...

BACKGROUND AND PURPOSE Previous studies reported that Tat-NR2B9c, a peptide disrupting the N-methyl-d-aspartate receptor-postsynaptic density protein-95 interaction, reduced ischemic damage in the acute phase after stroke. However, its effect in the subacute phase is unknown. The aim of this study is to determine whether disrupting the N-methyl-d-aspartate receptor-postsynaptic density protein-...

BACKGROUND AND PURPOSE We hypothesized that comorbid amyloid-beta (Aβ) deposition played a key role in long-term cognitive decline in subjects with stroke/transient ischemic attack. METHODS We recruited 72 subjects with cognitive impairment after stroke/transient ischemic attack to receive Carbon-11-labeled Pittsburgh compound B positron emission tomography. We excluded subjects with known cl...

The aim of the present study was to evaluate critically the protection afforded by hypothermia against ischemic injury to the hippocampus. Hypothermic treatment was applied selectively to the brain during a 5 min carotid artery occlusion in gerbils. Following a period of recovery, two independent measures were used to assess hippocampal function: (1) an open field test of spatial memory (assess...