objective (s) porin is a mitochondrial outer membrane channel, which usually functions as the pathway for the movement of various substances in and out of the mitochondria and is considered to be a component of the permeability transition (pt) pore complex that plays a role in the pt. we addressed the hypothesis that porin interacts with other mitochondrial proteins after ischemic injury. mater...

objective(s): electrical inhomogeneity between ischemic and non ischemic myocardium is the basis of arrhythmia which occurs following coronary artery occlusion. the leakage of potassium from the ischemic region to the non ischemic region is very effective in the generation of these arrhythmias. the aim of this study is to research the effect of atp-dependent potassium (katp) channel blocker (gl...

Abstract Zinc ion is essential for normal brain function that modulates synaptic activity and neuronal plasticity it associated with memory formation. considered to be a contributing factor the pathogenesis of ischemia, but association between zinc ischemia on vesicular exocytosis unclear. In this study, we used combination chemical analysis methods cell model ischemia/reperfusion investigate e...

Ischemia/reperfusion injury (I/R) is commonly related to acute kidney (AKI) and oxidative stress. Antioxidant agents are used treat this condition. Lippia sidoides a brazillian shrub with anti-inflammatory anti-oxidative properties. Thus, the aim of study evaluate effect ethanolic extract (LSEE) on in vivo vitro models AKI induced by I/R. Male Wistar rats were submitted unilateral nephrectomy i...

Recent studies have shown that renal ischemia-reperfusion injury can detrimental effects on distant organs such as the brain, liver and lungs. In this study, we aimed to investigate of pancreatic functions.
 Materials Methods. Twenty four male adult Wistar rats were divided into groups. Sham control group animals not given any medications. Animals in groups 3 4 treated with epidural bupiva...

conclusions our findings indicate that fullerenol nanoparticles decrease the brain infarction through enhancement of the sod activity during cerebral ischemia-reperfusion injury. results occlusion of mca induced considerable infarction and lesion in ischemic hemispheres of control ischemic rats (527 ± 59 mm3) in accompany with a decrease in the glutathione content (45%), and sod activity (29%) ...

renal ischemia-reperfusion (ir) contributes to the development of acute renal failure (arf). oxygen free radicals are considered to be principal components involved in the pathophysiological tissue alterations observed during renal ir. the purpose of this study was to investigate the combination effect of melatonin (mel) and erythropoietin (epo), which are a potent antioxidant and anti-apoptoti...

objective(s) the aim of this study was to investigate the overall effect of cardiac vasoactive factors during coronary occlusion and reperfusion on peripheral vascular tone, using a sequential isolated rabbit heart-ear perfusion model. materials and methods isolated ears were perfused with the effluent of isolated hearts subjected to ischemia (30 min) and reperfusion (180 min, n=6). the compara...

Mannitol is often administered during open juxtarenal or suprarenal aortic surgery to prevent ischemic injury the kidneys. Prior evidence evaluating benefits of intraoperative mannitol in reducing ischemia/reperfusion conflicting and largely based on small, retrospective series. The aim this study was evaluate effect preventing postoperative hemodialysis patients undergoing abdominal aneurysm (...

The Role of Uric Acid to HDL Cholesterol Ratio in Predicting Myocardial Ischemia Perfusion Scintigraphy Diabetic Patients
 Abstract
 Objective: Diabetes Mellitus (DM) is a significant risk factor for cardiovascular diseases, particularly myocardial ischemia. Both diabetes mellitus type 2 and conditions are characterized by high burden inflammation. uric High-Density Lipoprotein choles...