Albeit uncommon occurrence, irritant contact dermatitis induced by povidone iodine can be an unfortunate adverse reaction complicating its use as an antiseptic. We hereby present the case report of a patient who suffered such a reaction as a result of exposure to povidone iodine, employed as an antiseptic during spinal anesthesia. On conservative management with soframycin ointment, the lesions...

Cleansing and care of the diaper area require special consideration to maintain barrier function of the skin in this area and repair the barrier when it is compromised. Diaper dermatitis occurs commonly; understanding and modification of predisposing factors are imperative for caregivers. In this paper, we review important factors in diaper area care, including skin pH, the local microbiome, ir...

Patch testing is a well-established method of diagnosing contact allergy wherein patients with a history and clinical picture of contact dermatitis are re-exposed to the suspected allergens under controlled conditions to verify the diagnosis [1]. The results of first innovative patch-testing technique were presented by the German dermatologist, Josef Jadassohn (1863-1936) in 1895. The safety an...

Contact dermatitis is not a homogenous entity, but rather a number of subtypes contributing to different clinical presentations. For better understanding, instructional sheets provide information that assists in patient care. Informational sheets on contact dermatitis, patch testing, hand dermatitis, stasis dermatitis, and poison ivy are reviewed for open forum. Although often considered archai...

Contact dermatitis in pediatric population is a common but (previously) under recognized disease. It is usually divided into the allergic and the irritant forms. The diagnosis is usually obtained with the patch test technique after conducting a thorough medical history and careful physical examination but patch testing in infants may be particularly difficult, and false-positive reactions may o...

To assess the consequences of oxidative stress in allergic and irritant contact dermatitis, we compared the iron level, unsaturated iron-binding capacity, total iron binding capacity, the percentage saturation of iron-binding capacity, the amount of diene conjugates as well as the amounts of total glutathione, reduced glutathione, oxidized glutathione, and the oxidized glutathione/reduced gluta...

The FDA Adverse Events Reporting System (FAERS) is a computerized database of adverse events submitted by product manufacturers, consumers, and health care professionals. repository part the agency’s post-marketing safety surveillance program with relatively few published dermatologic-related reports. We analyzed FAERS public data base using search terms “dermatitis, contact” sorted as whole fr...

BACKGROUND Perfluoropolyethers (PFPEs) are non-reactive perfluorinated (no hydrogen atoms) liquid polymers that showed promise as ingredients of protective preparations in occupational dermatology. OBJECTIVE The aim of this study was to investigate if oil-in-water (o/w) emulsions containing 0.5, 1.0, 2.0 and 4.0% PFPEs (molecular weight 6,250 D) prevent epidermal barrier disruption induced by...

of the hair follicles) and differentiates it from the other conditions.5 Histology of tissue obtained by curettage of a papule is sufficient to establish the definitive diagnosis. Although there are reports of GP that resolved spontaneously once the irritant was eliminated, the lesions usually persist. A number of therapeutic modalities, including topical and oral preparations of retinoids, vit...

Conflicts of interest: The authors have declared no conflicts. hands, legs below knee level, and the area between the shoulder blades (Fig. 1). The patient had no history of dermatological disease and no prior or present exposure to sunlight, infection, or drugs. Biochemical screening was normal, skin cultures were negative, and a biopsy from lesional skin showed changes compatible with dermati...