Currently there are no satisfactory methods for estimating dietary iron absorption (bioavailability) at a population level, but this is essential for deriving dietary reference values using the factorial approach. The aim of this work was to develop a novel approach for estimating dietary iron absorption using a population sample from a sub-section of the UK National Diet and Nutrition Survey (...

BACKGROUND High body iron stores may increase the risk of several chronic diseases. Whether dietary factors contribute to the risk of high iron stores is unknown. OBJECTIVE We assessed the relation between dietary factors and the risk of high iron stores in the elderly Framingham Heart Study cohort. DESIGN We examined the relation between the usual intake of dietary factors (food-frequency ...

BACKGROUND In many developing countries, cereal and legume-based diets contain low amounts of bioavailable iron, which may increase the risk of iron deficiency. OBJECTIVE The objective was to measure change in iron status in Moroccan children who consumed their habitual diet containing low amounts of bioavailable iron. DESIGN The design was a prospective, longitudinal, free-living cohort st...

Background : A satisfactory nutritional status, as a result of optimal food intake, before conception and during pregnancy, is important for a successful pregnancy. Objective : To evaluate the energy and nutrient intake before conception and at mid-gestation in a group of pregnant women (n 50) in relation to the Nordic Nutrition Recommendations (NNR). Design : Pre-pregnant diet was studied by a...

Red meat consumption has been positively associated with colorectal cancer; however, the biological mechanism underlying this relationship is not understood. Red meat is a major source of iron, which may play a role in colorectal carcinogenesis via increased crypt cell proliferation, cytotoxicity, and endogenous N-nitrosation. In a nested case-control study within the Prostate, Lung, Colorectal...

UNLABELLED Background Following a clinical evaluation of deferasirox (Exjade) it was concluded that, in addition to baseline body iron burden, ongoing transfusional iron intake should be considered when selecting doses. The 1-year EPIC study, the largest ever investigation conducted for an iron chelator, is the first to evaluate whether fixed starting doses of deferasirox, based on transfusiona...

I ron is the most abundant transitional metal in the body. It has long been recognized that iron overload can increase the risk of diabetes, particularly in iron-overload states such as hemochromatosis and recurrent transfusions in diseases like thalassemia. Furthermore, a large body of epidemiological evidence suggests that an increase in dietary iron (as heme, mainly from meat and meat produc...

D URING RECENT STUDY to determine the frequency of the different types of anemia present in “well” infants and children attending a Maternal-Child Health clinic in eastern Saudi Arabia, it was found that at least 98.4 percent of anemic children had iron deficiency which was due to inadequate dietary intake of iron. This report is to point out that many seeming failures to respond to iron may be...

A 37-year old woman was referred to our clinic with severe iron-deficiency anemia which failed to respond to iron replacement therapy. Continued blood loss and compliance problems were excluded. Since the patient reported a daily intake of two liters of black tea, it was suspected that the tea had adverse effects on intestinal iron absorption. When the patient stopped drinking black tea her bod...