OBJECTIVES We sought to determine whether abnormal myocardial blood flow (MBF) responses to the cold pressor test (CPT) in patients with various risk factors may involve different mechanisms that could lead to varying responses of short- and long-term administration of antioxidants. BACKGROUND There is a growing body of evidence that increased vascular production of reactive oxygen species ma...

in this study the chemical properties of b6c4si and c16 clusters connected vitamin c have been investigated using density functional theory (dft). nmr parameters and homo- lumo gap energy are calculated by using density functional method (b3lyp) with 6-311g* basis set. calculations show that homo- lumo gap energy of vitamin c decreases after connecting to b6c4si or c16 cluster decreasing of hom...

Objective: Aflatoxin is known as one of the most important mycotoxins that threatens of human life. The toxin is produced by Aspergillus species which are common cause of contamination of agricultural products. For this reason, the use of organic compounds has always been considered in order to inhibit the growth of fungi and production of toxin. The aim of this study was to investigate the eff...

introduction: the pathogenesis of diabetic disorders are unknown and may be multifactorial. one of the most important mechanisms of complications is glycosilation of proteins such as haemoglobin. structurally, vitamin c is similar to glucose and can act as glucose in many chemical reactions, therefore it may prevent non- enzymatic glycosilation of proteins such as haemoglobin and lipoproteins. ...

background: oxidative modification of low-density lipoprotein (ldl) appears to be an early step in the pathogenesis of atherosclerosis. meanwhile, myeloperoxidase (mpo)-catalyzed reaction is one of the potent pathway for ldl oxidation in vivo. the aim of this study was to evaluate in vitro antioxidant effects of vitamins c and e on ldl oxidation mediated by mpo. methods: mpo was isolated from f...

background: oxidative stress (os) in the follicular environment may affect on oocyte competence and antioxidant vitamins may modify its effects. objective: this study was conducted to examine the effect of dietary intake of vitamin a, c and e on os in follicular environment and assisted reproduction technology (art) outcomes. materials and methods: in this obsevationalprospective study, the int...

This case report describes the acute mastitis with signs of endotoxemia in 32-month-old Simmental cow, antimicrobial susceptibility Klebsiella pneumoniae isolated from a milk sample, and demonstrates effectiveness applied therapy. Case presentation included cow-lying syndrome together presence clinical accompanied by discoloration “clots” formation. Bacteriology finding K. antibiogram pointed t...

In glucose-6-phosphate-dehydrogenase deficiency (favism), exposure to oxidant agents can trigger hemolytic crises. The intravenous administration of very high doses vitamin C was proposed as a treatment for severe coronavirus disease 2019 (COVID-19) pneumonia. Unlike low doses, (>6 gr daily) promote H2O2 formation, oxidation hemoglobin methemoglobin and, eventually, anemia in patients with f...

background: intravenous drug users (ivdus) who share needles/syringes and practice sexual behaviors, are the most important group in the transmission of blood-borne infection diseases such as hepatitis c virus (hcv). therefore identification of prevalent high-risky behaviors among ivdus to detect the most route of transmission among them is essential to develop harm reduction programs among ivd...

diabetes is a major health problem worldwide. type ii diabetic patients are reported to have higher ferritin and lower vitamin c concentrations. considering the role of ascorbic acid in carnitine biosynthesis and the limited information on free carnitine correlations with ferritin and vitamin c levels in diabetic patients without microvascular complications, this case-control study was conducte...