OBJECTIVES In our study, the aim is to evaluate the use of Fresh-Frozen Plasma (FFP) in our emergency department and to assess its audit for transfusion. METHODS All the patients aged 18 and over who received FFP transfusion in the emergency department between March 1, 2013 and March 1, 2016 were included into the study. The audit of FFP use was evaluated by according to 'British Committee fo...

Diamond Blackfan anemia typically presents in infants and is often associated with many kinds of malformations. Severity of anemia often needs transfusional support in the first months of life. We describe here a patient with Diamond Blackfan anemia related to a RPL5 mutation. The patient had no physical abnormalities and experienced a very late onset of transfusion dependency.

A CCUSTOMED as we now are to thousands of polymorphisms useful as human chromosome markers, it is hard to realize that in the first quarter century of Mendelism there was only one good marker. I t is a l l the more remarkable that its simple mode of inheritance was not understood until the trait had been known for 25 years. The human blood groups were discovered at the turn of the century (LA...

BACKGROUND Every year, millions of people are exposed to avoidable, life-threatening risks through the trans-fusion of unsafe blood. AIM To determine the survival time of Treponema pallidum in banked donor blood. MATERIAL AND METHODS Two groups of male Wistar rats (group A and B) were inoculated intratesticularly with 0.5ml of artificially infected donor blood (final density of Nichols trep...

BACKGROUND American College of Surgeons Trauma Quality Improvement Best Practices recommends initial massive transfusion (MT) cooler delivery within 15 minutes of protocol activation, with a goal of 10 minutes. The current study sought to examine the impact of timing of first cooler delivery on patient outcomes. METHODS Patients predicted to receive MT at 12 Level I trauma centers were random...

I T HAS BEEN proved by many authors that polycythemia induced by blood transfusion reduces the peripheral reticulocyte count and inhibits erythropoiesis. #{176} In previous investigations on erythropoiesis We have observed that polycythemia causes the appearance in the plasma of an active substance, which is antagonistic to erythropoietin. The plasma obtained from polycythemic animals was injec...

Pursuit of pharmaceutical purity of the blood in the bag has led to a shrinking donor base and a significantly more expensive product. Decisions regarding new infectious marker testing and donor deferrals have typically been made emphasizing decreasing one specific risk without considering the effect the intervention will have on the overall safety and availability of blood transfusion. Regulat...

T he 3rd International Congress on Transfusion Medicine was organized by the High Institute for Research and Education in Transfusion Medicine (IRETM) and the Scientific Society of Blood Transfusion in Tehran, Iran on December 15–17, 2015. The World Health Organization (WHO), the International Society of Blood Transfusion (ISBT), the French Blood Establishment (L’Etablissement Français du Sang;...

BACKGROUND No cases of transfusion-transmitted syphilis have been described for over four decades. While there is mandatory transfusion screening for syphilis, the absence of transmission is in part ascribed to a low prevalence of syphilis in the blood donor population, the concomitant use of antibiotics in a high proportion of transfusion recipients, allied with poor survival of T. pallidum du...