Artificial insemination with donor sperm yields pregnancy rates similar to the general fertile population with the woman's age being the best predictor for success. This article reviews the indications for donor insemination and the current American Society for Reproductive Medicine guidelines for screening both the donors and recipients. For most women, timing the insemination the day after de...

BACKGROUND To gain more insight in whether failure of intrauterine insemination (IUI) treatment in patients with idiopathic subfertility could be related to diminished fertilization, the aim of this study is to compare the fertilization of an initial IVF procedure after six cycles of IUI and the fertilization of an initial IVF procedure without preceding IUI cycles in couples with idiopathic su...

BACKGROUND Almost all assisted reproductive technology (ART) and intrauterine insemination (IUI) treatments performed in Australia are subsidized through the Australian Government's universal insurance scheme, Medicare. In 2010 restrictions on the amount Medicare paid in benefits for these treatments were introduced, increasing patient out-of-pocket payments for fresh and frozen embryo ART cycl...

Cervical anatomy limits the use of transcervical intrauterine artificial insemination (TC AI) in sheep. We have developed an instrument to cope atraumatically with the cervix; although this instrument has not affected fertilization rate or pregnancy rate through Day 3, the effects on sperm transport and pregnancy after Day 3 are not known. The objective of the present study was to determine whe...

OBJECTIVE To determine the relationship between serum P levels on the day of hCG administration and ongoing pregnancy rates. DESIGN Retrospective study. SETTING University-affiliated private IVF. PATIENT(S) A total of 2,458 couples undergoing IUI. INTERVENTION(S) Ovarian stimulation with human recombinant FSH. MAIN OUTCOME MEASURE(S) Ongoing pregnancy and miscarriage rates. RESULT(S...

BACKGROUND Prediction models have been developed in reproductive medicine to help assess the chances of a treatment-(in)dependent pregnancy. Careful evaluation is needed before these models can be implemented in clinical practice. METHODS We systematically searched the literature for papers reporting prediction models in reproductive medicine for three strategies: expectant management, intrau...

BACKGROUND Many studies have been carried out to understand the effect of endometrial thickness on the reproductive outcome while the factors affecting the pattern itself are still unknown. OBJECTIVE To determine the factors such as age and the number of follicles that could affect the endometrial thickness Materials and Methods: This study was conducted as a retrospective study on 680 infert...

OBJECTIVE To evaluate the awareness and response of fertility clinics in the UK to the National Institute for Health and Care Excellence (NICE) guideline recommendation that intrauterine insemination (IUI) should not be offered routinely, in order to report on current practice in the UK. DESIGN Online questionnaire survey of fertility clinics in the UK regarding their current clinical practic...

There is limited literature on the influence of smoking and BMI on success rates after intrauterine insemination (IUI). As a result of a prospective cohort study we could investigate data from 1401 IUI cycles with partner semen and 1264 IUI cycles with donor semen, primary outcome being clinical pregnancy rate (CPR). Univariate statistical analysis showed significant influence of female BMI on ...

OBJECTIVE To assess procreative outcomes for HIV-positive men and women with seronegative partners. DESIGN Systematic review and meta-analysis. SETTING Not applicable. PATIENT(S) Twenty-four studies with extractable data for HIV-serodiscordant couples undergoing intrauterine insemination (IUI) or in vitro fertilization (IVF). INTERVENTION(S) None. MAIN OUTCOME MEASURE(S) PRIMARY OU...