AIM To investigate the influence of acute changes in intraocular pressure on the oxygen tension in the vicinity of the optic nerve head under control conditions and after intravenous administration of 500 mg of the carbonic anhydrase inhibitor dorzolamide. METHODS Domestic pigs were used as experimental animals. Oxygen tension was measured by means of a polarographic electrode in the vitreous...

About 1 diopter (D) myopic change was induced experimentally in rabbit eyes by raising the body temperature and increasing the intraocular pressure with a specially designed suction cup. The myopic changes only took place when the body temperature was 41 to 43° C, intraocular pressure was above 40 mm. Hg, and topical atropine was given. Eyes subjected to repeated high pressure after the initial...

The effect on intraocular pressure (IOP) from dogs pulling against a collar or a harness was evaluated in 51 eyes of 26 dogs. The force each dog generated while pulling against a collar or a harness was measured. Intraocular pressure measurements were obtained during application of corresponding pressures via collars or harnesses. Intraocular pressure increased significantly from baseline when ...

Base-line intraocular pressure was similar in the rabbit eye ivith a transected optic nerve and the opposite eye subjected to a sham operation. Hyperosmotic oral ethanol, at doses of 1.5 to 2.0 ml. per kilogram, lowered intraoctdar pressure significantly less in eyes with transected optic nerves than in their fellow eyes with intact optic nerves. Smaller doses of ethanol (0.75 ml. per kilogram)...

purpose: to compare corneal biomechanical properties and intraocular pressure (iop) in eyes with pseudophakic bullous keratopathy (pbk) before and after descemet stripping automated endothelial keratoplasty (dsaek). methods: this prospective non-randomizedintrasubject comparative study was conducted on 44eyes of 22 patients with the diagnosis ofpbk who underwent dsaek in one eye.intraocular pre...

1. Nissen, O. I., and Hoppe, R.: The facility of aqueous outflow calculated from the rate of fall in applanation pressure after intravenous acetazolamide in man, Acta Ophthalmol. 52: 390, 1974. 2. Nissen, O. I.: The immediate response in applanation pressure to intravenous acetazolamide in primary glaucomas and glaucoma suspects, Acta Ophthalmol. 53: 537, 1975. 3. Grant, W. M.: Tonographic meth...

A new method has been devised for continual monitoring of intraocular pressure by radiotelemetry. The use of this instrument for monitoring intraocular pressure by a variety of ophthalmic conditions is described.

Topical administration of 1% vanadate in a formulation designed to enhance penetration lowered intraocular pressure in monkeys' eyes. The decrease in intraocular pressure was associated with significant decreases in aqueous humor flow. Tonographic outflow facility was unaltered by topical vanadate.

.he first report of a decrease in intraocular pressure following smoking of marihuana was received with a fair amount of skepticism, mirth, and bad publicity in the press, such as articles informing the public of a new "cure" for glaucoma. Now that the smoke has cleared, it is time to evaluate the effects of marihuana on the eye and make an objective assessment of the potential therapeutic valu...