The objective of this meta-analysis is to assess the impact of LH supplementation in women undergoing in vitro fertilization/ intracytoplasmic sperm injection (IVF/ICSI) with gonadotropin releasing hormone (GnRH) antagonist protocol. No significant difference in outcomes between LH supplementation and r-FSH alone in women undergoing IVF/ICSI with GnRH antagonist protocol is currently present, a...

Objective: Reproductive biotechnology studies focus on the longterm storage of embryos (cryopreservation), embryo cultures, genome editing and transfer. Micromanipulation techniques in reproduction biotechnologies have an important role, especially investigating assisted reproductive technology laboratory animals. The aim present study was to investigate effect epididymal spermatozoa injected o...

Hyaluronic acid (HA)-binding is reported to predict the fertilising capacity of spermatozoa, while HA-bound sperm selection reduce incidence miscarriage. However, clinical effectiveness these techniques remains uncertain. This work investigated prognostic value sperm-HA binding (HAB) as a predictor treatment outcomes, and whether HAB-sperm for Invitro fertilisation (IVF)/intracytoplasmic inject...

There is now considerable discussion whether intracytoplasmic sperm injection (ICSI) should be used in all cases of IVF. A critical and balanced view of the current literature is presented. The difficult question is how to identify men with apparently normal semen who are likely to fail to achieve a pregnancy using IVF. In conclusion, from both the safety and scientific viewpoint, ICSI should o...

In this paper, the development of a computer controlled piezo manipulation system for biomedical applications such as intra-cytoplasmic sperm injection (ICSI) is presented. The hardware setup and the control strategies will be described in full details to illustrate the advantages of this approach as compared to other manual-based injection methods.

With the introduction of intracytoplasmic sperm injection (ICSI), couples with severe male factor infertility have achieved fertilization and clinical pregnancy rates comparable to other in-vitro fertilization (IVF) patients. However, failure of fertilization still occurs in some patients despite the utilization of microsurgical sperm injection techniques. How such fertilization failure after I...

In this preliminary report, we describe a new technique involving the same-day transfer of activated oocytes to the uterus after intracytoplasmatic sperm injection (ICSI). The technique, termed activated oocyte transfer (AOT), offered to 19 couples, yielded a pregnancy rate per cycle of about 30%, equivalent to traditional in-vitro fertilization (IVF) and ICSI in a laboratory setting. AOT is pe...

Introduction Cryptozoospermia is defined by the World Health Organization (WHO) as presence of isolated sperm cell in ejaculate only identified after an extended microscopic search or being pelleted. Although number spermatozoa usually sufficient for intracytoplasmic injection (ICSI), ICSI fails due to poor quality some cases. Contention remains regarding whether testicular offers any advantage...

UNLABELLED The aim of this study was to measure circulating and intrafollicular concentrations of three inflammatory cytokines from women undergoing ovarian stimulation in order to determine their prognostic value in the outcome of intracytoplasmic sperm injection/embryo transfer cycles. MATERIALS AND METHODS A total of 72 women following ovarian stimulation and intracytoplasmic sperm injecti...